Recombinant Human Regenerating Islet-Derived 1 Beta, His-tagged

• Cat.No.: REG1B-3919H
• Product Overview: A DNA sequence encoding the human REG1B ( NP_006498.1 ) ( Met 1-Asn 166 ) was fused with a polyhistidine tag at the C-terminus.

Specification

• Cat. No.: REG1B-3919H
• Description: Regenerating gene, first isolated from a regenerating islet Cdna library, encodes a secretory protein with a growth stimulating effect on pancreatic beta cells. Reg and Reg-related genes which were expressed in various organs have been revealed to constitute a multigene family, the Reg family consisting of four subtypes ( types I, II, III, IV ) and are involved in cancers and neurodegenerative diseases.
• Source: Human
• Host: Human Cells
• Form: Supplied as a 0.2 μm filtered solution of PBS, pH 7.4
• Purity: > 95 % as determined by SDS-PAGE
• Endotoxin: < 1.0 EU per μg protein as determined by the LAL method
• Stability: Samples are stable for up to twelve months from date of receipt at -70°C.
• Predicted N terminal: Gln 23
• Molecular Mass: The recombinant human REG1B consists of 155 amino acids and predictes a molecular mass of 17.7 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh REG1B is approximately 19-21 kDa due to different glycosylation.
• Storage: Store it under sterile conditions at -70°C upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage.

Gene Information

• Gene Name: REG1B regenerating islet-derived 1 beta [ Homo sapiens ]
• Official Symbol: REG1B
• Synonyms: REG1B; regenerating islet-derived 1 beta; REGH; REGL; PSPS2; REGI-BETA; lithostathine-1-beta; PSP-2; REG-1-beta; OTTHUMP00000160488; lithostathine 1 beta; pancreatic stone protein 2; regenerating protein I beta; secretory pancreatic stone protein 2; regenerating islet-derived protein 1-beta; regenerating islet-derived 1 beta (pancreatic stone protein, pancreatic thread protein)
• Gene ID: 5968
• mRNA Refseq: NM_006507
• Protein Refseq: NP_006498
• MIM: 167771
• UniProt ID: P48304
• Chromosome Location: 2p12
• Function: binding; sugar binding