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Recombinant Human SECTM1 protein, His-tagged

Cat.No. : SECTM1-3967H
Product Overview : Recombinant Human SECTM1 (Gln29-Gly145) protein was fused to His-tag at C-terminus and expressed in human 293 cells (HEK293).
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Description : Secreted and transmembrane protein 1 (SECTM1) is also known as Protein K-12, which is belongs to the SECTM family, which is Inducted by IFNG/IFN-gamma (at protein level). SECTM1 is detected at the highest levels in peripheral blood leukocytes and breast cancer cell lines. SECTM1 may be involved in thymocyte signaling.
Source : HEK293
Species : Human
Tag : His
Predicted N Terminal : Gln29
Form : Lyophilized from 0.22 μm filtered solution in PBS, pH7.4, 10% trehalose.
Molecular Mass : The protein has a calculated MW of 13.5 kDa. The protein migrates as 18-23 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Protein length : Gln29-Gly145
Endotoxin : Less than 1.0 EU per μg by the LAL method.
Purity : >92% as determined by SDS-PAGE.
Storage : For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20 to -70 centigrade for 12 months in lyophilized state;
-70 centigrade for 3 months under sterile conditions after reconstitution.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Gene Name : SECTM1
Official Symbol : SECTM1
Synonyms : SECTM1; secreted and transmembrane 1; secreted and transmembrane protein 1; K12; K12 protein; type 1a transmembrane protein
Gene ID : 6398
mRNA Refseq : NM_003004
Protein Refseq : NP_002995
MIM : 602602
UniProt ID : Q8WVN6

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Does SECTM1 protein interact with other proteins? 09/08/2023

The SECTM1 protein may interact with other proteins to fulfill its function. These interactions can involve various types of protein-protein interactions like electrostatic interactions, hydrogen bonding, etc. Understanding these interactions can help unravel the mechanism of action of the SECTM1 protein in cells.

How to design experiments to study the structure and function of SECTM1 protein? 06/05/2023

Studying the structure and function of the SECTM1 protein may require the design of a series of experiments, including biochemical and cell biology experiments. For example, its structure can be studied by nuclear magnetic resonance or X-ray crystal diffraction, and its function can be studied by gene knockout or knockdown techniques.

How to evaluate the potential of the SECTM1 protein as a drug target? 05/01/2023

Evaluating the potential of the SECTM1 protein as a drug target can involve several aspects, including its expression levels in organisms, its role in biological processes, and its changes in disease. In addition, factors such as ease of drug development for this protein and potential drug side effects need to be considered.

What is the pathological significance of SECTM1 protein? 04/08/2023

SECTM1 protein may play an important role in the development and progression of certain diseases. For example, changes in its expression levels may be related to the occurrence and development of tumors. Studying the pathological significance of the SECTM1 protein can help develop therapeutic strategies against this protein.

What are the effects of mutations or modifications in the SECTM1 protein on organisms? 06/29/2020

Mutations or modifications in the SECTM1 protein may affect its function and thus affect the organism. The specific effects may vary depending on the type and location of the mutation or modification and may involve various biological processes, such as growth and development, immune response, etc.

How is the expression level of SECTM1 protein regulated? 06/16/2020

The expression level of SECTM1 protein may be regulated by a variety of factors, including gene transcription, translation, post-transcriptional modifications, etc. Studying these regulatory mechanisms can help to understand the expression patterns of SECTM1 protein in organisms and its impact on biological processes.

Customer Reviews (3)

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Reviews
03/08/2023

    I've used a lot of brands, but this one is one of my favorites.

    04/15/2022

      The storage conditions of SECTM1 are simple, which is convenient for long-term storage and use.

      12/07/2020

        The expression level and stability are good, and will be repurchased.

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