Recombinant Human SerpinB1 protein, His-tagged
Cat.No. : | SerpinB1-3981H |
Product Overview : | Recombinant Human SerpinB1 protein(P30740)(Met1-Pro379), fused with His tag, was expressed in Insect Cells. |
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Source : | Insect Cells |
Species : | Human |
Tag : | His |
Form : | Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 8.0, 10% gly. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Molecular Mass : | The recombinant human SERPINB1 consists of 390 amino acids and migrates as an approximately 44 kDa band as predicted in SDS-PAGE under reducing conditions. |
Protein Length : | Met1-Pro379 |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
Purity : | > 90 % as determined by SDS-PAGE |
Storage : | Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Publication : |
NSP4, an elastase-related protease in human neutrophils with arginine specificity. (2012)
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Gene Name : | SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 [ Homo sapiens ] |
Official Symbol : | SerpinB1 |
Synonyms : | SERPINB1; serpin peptidase inhibitor, clade B (ovalbumin), member 1; ELANH2, serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 1; leukocyte elastase inhibitor; anti elastase; EI; PI2; PI-2; serpin B1; anti-elastase; peptidase inhibitor 2; monocyte/neutrophil elastase inhibitor; protease inhibitor 2 (anti-elastase), monocyte/neutrophil derived; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 1; LEI; MNEI; M/NEI; ELANH2; |
Gene ID : | 1992 |
mRNA Refseq : | NM_030666 |
Protein Refseq : | NP_109591 |
MIM : | 130135 |
UniProt ID : | P30740 |
Products Types
◆ Recombinant Protein | ||
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SERPINB1-3966R | Recombinant Rhesus Macaque SERPINB1 Protein, His (Fc)-Avi-tagged | +Inquiry |
SERPINB1-1975H | Recombinant Human SERPINB1 Protein, His (Fc)-Avi-tagged | +Inquiry |
SERPINB1-857H | Recombinant Human SERPINB1 Protein, MYC/DDK-tagged | +Inquiry |
SERPINB1-4149R | Recombinant Rhesus monkey SERPINB1 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
SERPINB1-578HCL | Recombinant Human SERPINB1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionIt inhibits neutrophil elastase and cathepsin G, balancing proteolysis.
Its expression and activity are regulated by various signaling pathways and transcription factors.
Potential therapeutic applications could involve modulating SERPINB1 to mitigate damage in inflammatory and infectious diseases.
It helps control inflammation by modulating protease activity in immune responses.
SERPINB1 functions as a serine protease inhibitor, regulating protease activity.
SERPINB1 protects tissues from damage during inflammation and infection.
SERPINB1 is predominantly expressed in neutrophils and some other immune cells.
Customer Reviews (3)
Write a reviewQuick, efficient, reliable service.
Worked great, highly pure.
Excellent for molecular experiments.
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