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Recombinant Human TFRC protein, His-tagged, Biotinylated

Cat.No. : TFRC-3864H
Product Overview : Recombinant Human TFRC protein(NP_003225.2)(Cys 89-Phe 760), fused with His tag, was expressed in HEK293.
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Source : HEK293
Species : Human
Tag : His
Form : Lyophilized from sterile PBS, pH 7.4Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Molecular Mass : The recombinant human TFRC consists of 689 amino acids and predicts a molecular mass of 77.4 kDa.
Protein Length : Cys 89-Phe 760
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method
Purity : > 85 % as determined by SDS-PAGE
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : TFRC transferrin receptor (p90, CD71) [ Homo sapiens ]
Official Symbol : TFRC
Synonyms : TFRC; transferrin receptor (p90, CD71); transferrin receptor protein 1; CD71; TFR1; T9; TR; TFR; p90; TRFR;
Gene ID : 7037
mRNA Refseq : NM_001128148
Protein Refseq : NP_001121620
MIM : 190010
UniProt ID : P02786

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can TFRC be used to develop targeted drug delivery systems? 09/13/2022

Yes, TFRC's presence on cell surfaces has been exploited for the development of targeted drug delivery systems, especially for delivering drugs to cancer cells.

Are there any therapies that target TFRC in cancer treatment? 11/17/2020

Yes, some experimental therapies aim to target TFRC on cancer cells, such as antibody-drug conjugates (ADCs) and small-molecule inhibitors.

Are there any clinical conditions associated with TFRC protein dysregulation? 09/19/2017

Yes, dysregulation of TFRC expression or function can be associated with various medical conditions, including anemia, cancer, and neurodegenerative diseases.

How is TFRC protein studied in clinical research and diagnostics? 10/03/2016

Researchers use techniques like immunohistochemistry and molecular assays to study TFRC expression levels in patient samples. This helps in diagnosis and prognosis.

How can TFRC be relevant in the treatment of iron-deficiency anemia? 01/02/2016

Understanding TFRC expression in the context of anemia can help identify the underlying causes and guide treatment strategies to improve iron uptake.

Customer Reviews (3)

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09/06/2021

    In addition to the advantages of GAD1 protein itself, the manufacturer can play a crucial role in supporting the research efforts.

    04/19/2018

      This quality control is essential for obtaining reliable and reproducible data, as any variability in protein quality can introduce confounding factors into experiments.

      01/27/2017

        This versatility enables researchers to explore GAD1's function and role in a range of biological processes, making it a valuable tool across diverse research fields.

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