Active Recombinant Human IL2
Cat.No. : | IL2-341H |
Product Overview : | Human IL2 (NP_000577, 22 a.a.-153 a.a.) partial recombinant protein expressed in Escherichia coli. |
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Cat. No. : | IL2-341H |
Description : | Interleukin-2 (IL-2) is an interleukin, a type of cytokine immune system signaling molecule, which is a leukocytotrophic hormone that is instrumental in the body"s natural response to microbial infection and in discriminating between foreign (non-self) and self. IL-2 mediates its effects by binding to IL-2 receptors, which are expressed by lymphocytes, the cells that are responsible for immunity. |
Sequence : | MPTSSSTKKT QLQLEHLLLD LQMILNGINN YKNPKLTRML TFKFYMPKKA TELKHLQCLE EELKPLEEVL NLAQSKNFHL RPRDLISNIN VIVLELKGSE TTFMCEYADE TATIVEFLNR WITFSQSIIS TLT |
Theoretical MW (kDa) : | 15.4 |
Form : | Liquid |
Preparation Method : | Escherichia coli expression system |
Purity : | > 95% by SDS-PAGE |
Activity : | Measured in a cell proliferation assay using CTLL2 mouse cytotoxic T cells. The ED50 for this effect is < 1.5 ng/mL. |
Application : | SDS-PAGE |
Storage Buffer : | In PBS, pH 7.4 |
Storage : | Store at 4°C for 1-2 weeks. For long term storage store at -20°C or -80°C. Aliquot to avoid repeated freezing and thawing. |
Unitprot ID : | P60568 |
Pathways : | Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway; T cell receptor signaling pathway; Type I diabetes mellitus |
Publication : |
Cytokine and reactivity profiles in SLE patients following anti-CD19 CART therapy (2023)
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Gene Name : | IL2 interleukin 2 [ Homo sapiens ] |
Official Symbol : | IL2 |
Synonyms : | IL-2; TCGF; lymphokine; T-cell growth factor; Aldesleukin, Interleukin-2; interleukin-2 precursor; involved in regulation of T-cell clonal expansion; IL2; interleukin 2 |
Gene ID : | 3558 |
mRNA Refseq : | NM_000586 |
Protein Refseq : | NP_000577 |
MIM : | 147680 |
Chromosome Location : | 4q26-q27 |
Function : | interleukin-2 receptor binding; kinase activator activity |
Products Types
◆ Recombinant Protein | ||
Il2-028I | Active Recombinant Mouse Il2 Protein (149 aa) | +Inquiry |
IL2-169H | Active Recombinant Human IL2 Protein, His-tagged(C-ter) | +Inquiry |
IL2-349H | Recombinant Human IL2 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
IL2-41H | Recombinant Human IL2 Protein | +Inquiry |
IL2-02R | Recombinant Rabbit IL2 Protein | +Inquiry |
◆ Lysates | ||
IL2-5234HCL | Recombinant Human IL2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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