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Human Cystatin C 1r4c

Cat.No. : CST3-3667H
Product Overview : Native protein isolated from human urine.
  • Specification
  • Gene Information
  • Related Products
Cat. No. : CST3-3667H
Description : Cystatin C is mainly used as a biomarker of kidney function. Recently, it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease. It also seems to play a role in brain disorders involving amyloid. In humans, all cells with a nucleus (cell core containing the DNA) produce cystatin C as a chain of 120 amino acids. It is found in virtually all tissues and bodily fluids. It is a potent inhibitor of lysosomal proteinases and probably one of the most important extracellular inhibitors of cysteine proteases. Cystatin C belongs to the type 2 cystatin gene family.
Source : Native
Species : Human
Form : Filtered (0,4 μm) and lyophilised from 0.6 mg/mL in 20mM NH4HCO3 with traces of buffer salts.
Research topic : Renal disease
Purity : >96%
Reconstitution : Add 20mM NH4HCO3 to prepare a working stock solution of approximately 0.5 mg/mL. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.
Applications : Western blotting; ELISA
Quality Control Test : BCA to determine quantity of the protein; SDS PAGE to determine purity of the protein
Storage : Store lyophilized protein at -20°C. Lyophilized protein remains stable until the expiry date when stored at -20°C. Aliquot reconstituted protein to avoid repeated freezing/thawing cycles and store at -80°C for long term storage. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after one week at 4°C.
Pathways : Salivary secretion
Gene Name : CST3 cystatin C [ Homo sapiens ]
Official Symbol : CST3
Synonyms : CST3; cystatin C; ARMD11; MGC117328; cystatin 3; cystatin-3; gamma-trace; OTTHUMP00000030440; OTTHUMP00000164181; OTTHUMP00000164182; post-gamma-globulin; bA218C14.4 (cystatin C); neuroendocrine basic polypeptide; cystatin C (amyloid angiopathy and cerebral hemorrhage); Cystatin-C; Gamma-trace; Neuroendocrine basic polypeptide; Post-gamma-globulin
Gene ID : 1471
mRNA Refseq : NM_000099
Protein Refseq : NP_000090
MIM : 604312
UniProt ID : P01034
Chromosome Location : 20p11.2
Function : beta-amyloid binding; cysteine-type endopeptidase inhibitor activity; peptidase inhibitor activity; protease binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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