| Cat. No. | CABT-21885MH |
| Antigen Description | The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene. |
| Product Overview | Mouse monoclonal antibody raised aganist full length recombinant HAX1. |
| Immunogen | Recombinant protein corresponding to full length human HAX1. |
| Isotype | IgG2b, kappa |
| Application | Western Blot, ELISA |
| Form | Liquid |
| Storage Buffer | In PBS, pH 7.4 (0.1% sodium azide) |
| Reactivity | Human |
| Recommend Usage | The optimal working dilution should be determined by the end user. |
| Note | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Clone | BU4D6 |
| Host | Mouse |
| Antigen Gene Information | Gene Name | HAX1 HCLS1 associated protein X-1 [Homo sapiens] |
| Official symbol | HAX1 |
| Synonyms | HCLS1 associated protein X-1; FLJ17042; HS1BP1; FLJ18492; HCLSBP1; FLJ93803; OTTHUMP00000034191; HSP1BP-1; OTTHUMP00000034192; HS1-associating protein X-1; HCLS1 (and PKD2) associated protein; HS1-binding protein 1; HCLS1-associated protein X-1; SCN3; HS1 binding protein; HAX-1; OTTHUMP00000034190; OTTHUMP00000231810; OTTHUMP00000231812 |
| GeneId | 10456 |
| mRNA Refseq | NM_001018837 |
| Protein Refseq | NP_001018238 |
| MIM | 605998 |
| Uniprot ID | O00165 |
| Chromosome Location | 1q21.3 |
| Function | interleukin-1 binding; protein N-terminus binding; protein binding |
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