Recombinant Human Cathepsin K
Cat.No. : | CTSK-1659H |
Product Overview : | Recombinant human CTSK is a 35.1 kDa homodimeric protein consisting of 99 amino acid polypeptide domain. |
- Specification
- Gene Information
- Related Products
Cat. No. : | CTSK-1659H |
Description : | CTSK is a member of the papain cysteine proteinase family and has been identified as the predominant proteinase responsible for the resorption of the bone matrix. The enzyme cleaves proteins such as collagen type I, collagen type II and osteonectin and therefore plays a role in bone remodeling and resorption in diseases such as osteoporosis, osteolytic bone metastasis and rheumatoid arthritis. |
Molecular Weight : | 35.1 kDa |
Source : | E. Coli |
Species : | Human |
Form : | Liquid (25 mM Tris pH 8.0, 500 mM NaCl). |
Appearance : | Liquid |
Purity : | ≥95% by SDS-PAGE |
Storage : | Procathepsin K can be aliquoted and stored at -80°C. Repeated freeze-thaw cycles must be avoided. |
Gene Name : | CTSK cathepsin K [ Homo sapiens ] |
Official Symbol : | CTSK |
Synonyms : | CTSK; cathepsin K; CTSO; PKND; PYCD; CTS02; CTSO1; CTSO2; MGC23107; cathepsin K; cathepsin O; cathepsin X; cathepsin O1; cathepsin O2; OTTHUMP00000032938 |
Gene ID : | 1513 |
mRNA Refseq : | NM_000396 |
Protein Refseq : | NP_000387 |
MIM : | 601105 |
UniProt ID : | P43235 |
Chromosome Location : | 1q21 |
Pathway : | Lysosome; Osteoclast Signaling; Osteoclast differentiation; Rheumatoid arthritis; Toll-like receptor signaling pathway |
Function : | cysteine-type endopeptidase activity; cysteine-type peptidase activity; peptidase activity |
Products Types
◆ Recombinant Protein | ||
CTSK-439R | Recombinant Rat CTSK Protein (115-329 aa), His-tagged | +Inquiry |
CTSK-440R | Active Recombinant Rat Ctsk Protein | +Inquiry |
CTSK-914R | Recombinant Rhesus Macaque CTSK Protein, His (Fc)-Avi-tagged | +Inquiry |
CTSK-2069M | Recombinant Mouse CTSK Protein, His (Fc)-Avi-tagged | +Inquiry |
CTSK-2111H | Recombinant Human CTSK Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
CTSK-7192HCL | Recombinant Human CTSK 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-2352 | Cathepsin K Inhibitor Screening Kit (Fluorometric) | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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