Recombinant Mouse Nicotinamide Phosphoribosyltransferase

• Cat.No.: Nampt-1667M
• Product Overview: Recombinant full-length (a.a.1-491) mouse Nampt was expressed in E. coli, 55 kDa.

Specification

• Cat. No.: Nampt-1667M
• Description: Nicotinamide phosphoribosyltransferase (NAmPRTase or Nampt) also known as pre-B-cell colony-enhancing factor 1 (PBEF1) or visfatin is an enzyme that in humans is encoded by the PBEF1 gene.This protein has also been reported to be a cytokine (PBEF) that promotes B cell maturation and inhibits neutrophil apoptosis.
• Biological Activity: Mimics insulin effects in differentiating 3T3-L1 cells.
• Molecular Weight: 55 kDa
• Source: E. coli
• Species: Mouse
• Form: Lyophilized without additives.
• Appearance: Lyophilized protein
• Endotoxin Level: <0.1 ng/μg
• Reconstitution: Reconstitute in PBS to the concentration of 0.1-1 mg/ml.
• Purity: >95% by SDS-PAGE and HPLC.
• Storage: -20°C.
• Pathways: Adipogenesis; Metabolism of vitamins and cofactors; Metabolism of water-soluble vitamins and cofactors; NAD biosynthesis III; Nicotinamide salvaging; Nicotinate and nicotinamide metabolism; Nicotinate metabolism

Gene Information

• Gene Name: Nampt nicotinamide phosphoribosyltransferase [ Mus musculus ]
• Official Symbol: Nampt
• Synonyms: Nampt; nicotinamide phosphoribosyltransferase; Pbef; Pbef1; AI314458; AI480535; Visfatin; NAmPRTase; 1110035O14Rik; pre-B-cell colony-enhancing factor 1 homolog; NP_067499.2; EC 2.4.2.12; DKFZp666B131; pre-B-cell colony enhancing factor 1; MGC117256; Pre-B cell-enhancing factor; OTTHUMP00000179150
• Gene ID: 59027
• mRNA Refseq: NM_021524
• Protein Refseq: NP_067499
• UniProt ID: Q99KQ4
• Chromosome Location: 12; 12 B1
• Function: cytokine activity; drug binding; nicotinamide phosphoribosyltransferase activity; nicotinate phosphoribosyltransferase activity; nicotinate-nucleotide diphosphorylase (carboxylating) activity; protein homodimerization activity; transferase activity; transferase activity, transferring glycosyl groups