Recombinant Rat Nicotinamide Phosphoribosyltransferase
Cat.No. : | Nampt-1668R |
Product Overview : | Recombinant full-length (a.a.27-491)mouse Nampt was expressed in E.coli, 53kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | Nampt-1668R |
Description : | Nicotinamide phosphoribosyltransferase (NAmPRTase or Nampt) also known as pre-B-cell colony-enhancing factor 1 (PBEF1) or visfatin is an enzyme that in humans is encoded by the PBEF1 gene.This protein has also been reported to be a cytokine (PBEF) that promotes B cell maturation and inhibits neutrophil apoptosis. |
Biological Activity : | Mimics insulin effects in differentiating 3T3-L1 cells. |
Molecular Weight : | 53 kDa |
Source : | E. coli |
Species : | Rat |
Form : | Lyophilized without additives. |
Appearance : | Lyophilized protein |
Endotoxin Level : | <0.1 ng/μg |
Reconstitution : | Reconstitute in PBS to the concentration of 0.1-1 mg/ml. |
Purity : | >95% by SDS-PAGE. |
Storage : | -20°C. |
Pathways : | Adipogenesis; Metabolism of vitamins and cofactors; Metabolism of water-soluble vitamins and cofactors; Nicotinamide salvaging; Nicotinate and nicotinamide metabolism; Nicotinate metabolism |
Gene Name : | Nampt nicotinamide phosphoribosyltransferase [ Rattus norvegicus ] |
Official Symbol : | Nampt |
Synonyms : | Nampt; nicotinamide phosphoribosyltransferase; Pbef; Pbef1; visfatin; NAmPRTase; pre-B-cell colony enhancing factor 1; pre-B-cell colony-enhancing factor 1 homolog |
Gene ID : | 297508 |
mRNA Refseq : | NM_177928 |
Protein Refseq : | NP_808789 |
UniProt ID : | Q80Z29 |
Chromosome Location : | 6q16 |
Function : | cytokine activity; drug binding; nicotinamide phosphoribosyltransferase activity; nicotinate phosphoribosyltransferase activity; nicotinate-nucleotide diphosphorylase (carboxylating) activity; protein homodimerization activity; transferase activity, transferring glycosyl groups |
Products Types
◆ Recombinant Protein | ||
NAMPT-3554R | Recombinant Rat NAMPT Protein, His (Fc)-Avi-tagged | +Inquiry |
NAMPT-2531H | Recombinant Human NAMPT protein(Met1-His491), His&GST-tagged | +Inquiry |
NAMPT-212H | Recombinant Human NAMPT Protein | +Inquiry |
NAMPT-3579H | Recombinant Human NAMPT Protein, His (Fc)-Avi-tagged | +Inquiry |
NAMPT-5900M | Recombinant Mouse NAMPT Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
NAMPT-491HCL | Recombinant Human NAMPT cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionThe types of mutations in NAMPT include point mutations, insertions/deletions, duplications, etc., which can cause structural and functional abnormalities of the protein.
Some diseases related to NAD+ metabolism can be treated by regulating the level of NAMPT, such as by inhibiting its activity or regulating its expression.
Studying the regulatory mechanism of NAMPT requires a comprehensive use of various experimental methods and techniques, such as gene knockout, transcriptome analysis, and protein-protein interactions.
NAMPT has a complex relationship with other genes or proteins, and can interact with other genes or proteins and participate in a variety of biochemical reactions.
NAMPT plays an important role in cellular energy metabolism by catalyzing the synthesis of NAD+, an important intracellular coenzyme involved in various reactions of energy metabolism.
Mutations in NAMPT can be detected and analyzed by methods such as whole-genome sequencing or target region sequencing to understand the impact of mutations on protein structure and function.
Customer Reviews (3)
Write a reviewDoes not trigger an immune response.
Methods such as ELISA or immunostaining perform well.
Easy to use, high stability, remarkable effect.
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