Recombinant Human CREB Binding Protein, GST-tagged
Cat.No. : | CREBBP-1581H |
Product Overview : | Recombinant human CREBBP (518-1207; contains the catalytic domain) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Cat. No. : | CREBBP-1581H |
Description : | CREBBP has intrinsic histone acetyltransferase activity that acts as a scaffold to stabilize additional protein interactions with the transcription complex and acetylates both histone and non-histone proteins. CREBBP expressed as a nuclear protein that binds to cAMP-response element binding protein (CREB) and involved in the transcriptional coactivation of many different transcription factors. CREBBP plays a main role in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. CREBBP also plays a critical role in the transmission of inductive signals from cell surface receptors to the transcriptional apparatus. |
Applications : | Western Blot |
Molecular Weight : | 140 kDa |
Expression System : | Sf9 insect cells using baculovirus |
Species : | Human |
Form : | Recombinant protein stored in 50 mM Tris-HCl, ph 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25 % glycerol. |
Purity : | > 90 % |
Concentration : | 0.1 ug/ul |
Sequences : | 518-1207 |
Storage : | Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Pathways : | Adherens junction; Cell cycle; Huntington"s disease; Jak-STAT signaling pathway; Long-term potentiation; Notch signaling pathway; Pathways in cancer; Prostate cancer; Renal cell carcinoma; Melanogenesis; TGF-beta signaling pathway; Wnt signaling pathway; Gene Expression; Metabolism of lipids and lipoproteins |
Gene Name : | CREBBP CREB binding protein [ Homo sapiens ] |
Official Symbol : | CREBBP |
Synonyms : | CREBBP; CREB binding protein; CBP; RSTS; KAT3A; Rubinstein-Taybi syndrome; RTS; CREB-binding protein; OTTHUMP00000159801; NP_001073315.1; EC 2.3.1.48; NP_004371.2 |
Gene ID : | 1387 |
mRNA Refseq : | NM_004380 |
Protein Refseq : | NP_004371 |
MIM : | 600140 |
UniProt ID : | Q92793 |
Chromosome Location : | 16p13.3 |
Function : | MyoD binding; SMAD binding; acetyltransferase activity; histone acetyltransferase activity; metal ion binding; p53 binding; peroxisome proliferator activated receptor binding; signal transducer activity; transcription coactivator activity; transcription coactivator activity; transcription factor activity; transferase activity; zinc ion binding |
Products Types
◆ Recombinant Protein | ||
CREBBP-22HCL | Recombinant Human CREBBP 293 Cell Lysate | +Inquiry |
CREBBP-1852H | Recombinant Human CREBBP Protein, GST-tagged | +Inquiry |
CREBBP-1022R | Recombinant Monkey Crebbp Protein, His tagged | +Inquiry |
CREBBP-847R | Recombinant Rhesus Macaque CREBBP Protein, His (Fc)-Avi-tagged | +Inquiry |
CREBBP-001H | Recombinant Human CREBBP Protein, GST-tagged | +Inquiry |
◆ Assay kits | ||
Kit-1710 | CREBBP Inhibitor Screening Assay Kit | +Inquiry |
Kit-1711 | CREBBP TR-FRET Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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