| Cat. No. : |
ELK1-4841H |
| Description : |
ELK1 is a member of the ETS oncogene family of transcription factors. ELK1 protein interacts with promoter of the c-fos proto-oncogene and has been shown to be involved in the Ras-Raf-MAPK signaling cascade. Immature phosphorylation of transcription factor ELK-1 is implicated in premature aging syndrome and insulin resistance. Expression studies have revealed that elevated expression of ELK1-like protein in human esophageal can result in squamous cell carcinoma. |
| Applications : |
Kinase Assay; Western Blot |
| Molecular Weight : |
81 kDa |
| Expression System : |
E. coli |
| Species : |
Human |
| Form : |
Recombinant protein stored in 50 mM Tris-HCl, ph 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25 % glycerol. |
| Purity : |
> 75 % |
| Concentration : |
0.2 ug/ul |
| Sequences : |
Full length |
| Storage : |
Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
| Pathways : |
Activated TLR4 signalling; BCR signaling pathway; EGFR1 Signaling Pathway; ERK/MAPK targets; Endometrial cancer; ErbB signaling pathway; ErbB signaling pathway; ErbB signaling pathway; Focal Adhesion; GnRH signaling pathway; HTLV-I infection; IL-4 signaling Pathway; IL-5 Signaling Pathway; Id Signaling Pathway; Insulin Signaling |
