Recombinant Mouse Histone Deacetylase 5, GST-tagged
Cat.No. : | Hdac5-1593M |
Product Overview : | Recombinant mouse Hdac5 (617-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Cat. No. : | Hdac5-1593M |
Description : | Hdac5 or Histone deacetylase 5 belongs to the class II histone deacetylase/acuc/apha family that possesses histone deacetylase activity and represses transcription when tethered to a promoter. Hdac5 plays a critical role in transcriptional regulation, cell cycle progression, and developmental events and also acts as a potential therapeutic target for the prevention of atherosclerosis. |
Applications : | HDAC Assay; Western Blot |
Molecular Weight : | 80 kDa |
Expression System : | Sf9 insect cells using baculovirus |
Species : | Mouse |
Form : | Recombinant protein stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol. |
Purity : | >90% |
Concentration : | 0.1 ug/ul |
Specific Activity : | 110 RLU/min/ng |
Sequences : | 617-end |
Storage : | Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Gene Name : | Hdac5 histone deacetylase 5 [ Mus musculus ] |
Official Symbol : | Hdac5 |
Synonyms : | Hdac5; histone deacetylase 5; Hdac4; mHDA1; AI426555; mKIAA0600; histone deacetylase 5; HD5; OTTMUSP00000002428; OTTMUSP00000030249; OTTMUSP00000030251; histone deacetylase 4; histone deacetylase mHDA1 |
Gene ID : | 15184 |
mRNA Refseq : | NM_001077696 |
Protein Refseq : | NP_001071164 |
UniProt ID : | Q6P9T4 |
Chromosome Location : | 11 |
Function : | histone deacetylase activity; hydrolase activity; protein binding; protein kinase C binding; repressing transcription factor binding; transcription corepressor activity; transcription factor binding |
Products Types
◆ Recombinant Protein | ||
HDAC5-164H | Recombinant Human HDAC5 Protein, His-tagged | +Inquiry |
HDAC5-312H | Active Recombinant Human HDAC5 Protein | +Inquiry |
HDAC5-1876R | Recombinant Rhesus Macaque HDAC5 Protein, His (Fc)-Avi-tagged | +Inquiry |
HDAC5-48H | Recombinant Human HDAC5 Protein, His-tagged | +Inquiry |
HDAC5-4647H | Recombinant Human HDAC5 Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
HDAC5-5604HCL | Recombinant Human HDAC5 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-1741 | HDAC5 Fluorogenic Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionIt has been linked to a variety of neurological diseases, including Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, etc. It influences the development of these diseases by regulating the function and survival of neurons.
This is also associated with cardiovascular disease. Studies have shown that HDAC5 can regulate the function and survival of the heart, influencing the development of heart disease.
HDAC5 is associated with a variety of diseases, including cancer, neurological diseases, cardiovascular diseases, etc.
The activity of HDAC5 is regulated by a variety of factors, including intracellular signaling, transcription factors, and other proteases.
HDAC5 inhibitors can enhance the sensitivity of tumor cells and improve the effectiveness of chemotherapy or radiotherapy. In addition, it can also inhibit the migration and invasion of tumor cells.
This protein plays an important role in cancer, affecting the occurrence and progression of tumors by regulating the expression of tumor suppressor genes and tumor progenes.
Customer Reviews (3)
Write a reviewThe HDAC5 they produce is of guaranteed quality, and we can rest assured that we buy it.
It performs well in ELISA and is very suitable for immunoassays.
It has strong antibacterial activity and is not easy to be contaminated.
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