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Recombinant Mouse Histone Deacetylase 5, GST-tagged

Cat.No. : Hdac5-1593M
Product Overview : Recombinant mouse Hdac5 (617-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
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  • Gene Information
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Cat. No. : Hdac5-1593M
Description : Hdac5 or Histone deacetylase 5 belongs to the class II histone deacetylase/acuc/apha family that possesses histone deacetylase activity and represses transcription when tethered to a promoter. Hdac5 plays a critical role in transcriptional regulation, cell cycle progression, and developmental events and also acts as a potential therapeutic target for the prevention of atherosclerosis.
Applications : HDAC Assay; Western Blot
Molecular Weight : 80 kDa
Expression System : Sf9 insect cells using baculovirus
Species : Mouse
Form : Recombinant protein stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
Purity : >90%
Concentration : 0.1 ug/ul
Specific Activity : 110 RLU/min/ng
Sequences : 617-end
Storage : Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Gene Name : Hdac5 histone deacetylase 5 [ Mus musculus ]
Official Symbol : Hdac5
Synonyms : Hdac5; histone deacetylase 5; Hdac4; mHDA1; AI426555; mKIAA0600; histone deacetylase 5; HD5; OTTMUSP00000002428; OTTMUSP00000030249; OTTMUSP00000030251; histone deacetylase 4; histone deacetylase mHDA1
Gene ID : 15184
mRNA Refseq : NM_001077696
Protein Refseq : NP_001071164
UniProt ID : Q6P9T4
Chromosome Location : 11
Function : histone deacetylase activity; hydrolase activity; protein binding; protein kinase C binding; repressing transcription factor binding; transcription corepressor activity; transcription factor binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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Is there a relationship between HDAC5 and neurological diseases? 11/26/2022

It has been linked to a variety of neurological diseases, including Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, etc. It influences the development of these diseases by regulating the function and survival of neurons.

What is the link between HDAC5 and cardiovascular disease? 04/17/2022

This is also associated with cardiovascular disease. Studies have shown that HDAC5 can regulate the function and survival of the heart, influencing the development of heart disease.

What is the relationship between HDAC5 and disease? 04/17/2022

HDAC5 is associated with a variety of diseases, including cancer, neurological diseases, cardiovascular diseases, etc.

How is HDAC5 activity regulated? 02/08/2021

The activity of HDAC5 is regulated by a variety of factors, including intracellular signaling, transcription factors, and other proteases.

Do HDAC5 inhibitors have a role in treatment? 07/07/2020

HDAC5 inhibitors can enhance the sensitivity of tumor cells and improve the effectiveness of chemotherapy or radiotherapy. In addition, it can also inhibit the migration and invasion of tumor cells.

Which role of HDAC5 in cancer? 01/21/2020

This protein plays an important role in cancer, affecting the occurrence and progression of tumors by regulating the expression of tumor suppressor genes and tumor progenes.

Customer Reviews (3)

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Reviews
02/22/2022

    The HDAC5 they produce is of guaranteed quality, and we can rest assured that we buy it.

    12/22/2021

      It performs well in ELISA and is very suitable for immunoassays.

      02/13/2020

        It has strong antibacterial activity and is not easy to be contaminated.

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