Recombinant Human Histone Deacetylase 8, His-tagged
Cat.No. : | HDAC8-1595H |
Product Overview : | Full-length recombinant human HDAC8 was expressed by baculovirus in Sf9 insect cells using a C-terminal His tag. |
- Specification
- Gene Information
- Related Products
Cat. No. : | HDAC8-1595H |
Description : | HDAC8 or Histone deacetylase 8 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. The protein encoded by this gene belongs to class I of the histone deacetylase family that catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. |
Applications : | HDAC Assay; Western Blot |
Molecular Weight : | 47 kDa |
Expression System : | Sf9 insect cells using baculovirus |
Species : | Human |
Form : | Recombinant protein stored in 50 mM MOPS, PH 7.0, 300 mM NaCI, 150 mM imidazole, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol. |
Purity : | >90% |
Concentration : | 0.05 ug/ul |
Specific Activity : | 1400 RLU/min/ng |
Sequences : | Full length |
Storage : | Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Pathways : | Signaling events mediated by HDAC Class I; Signaling events mediated by HDAC Class I |
Gene Name : | HDAC8 histone deacetylase 8 [ Homo sapiens ] |
Official Symbol : | HDAC8 |
Synonyms : | HDAC8; histone deacetylase 8; HD8; RPD3; CDA07; HDACL1; histone deacetylase 8; OTTHUMP00000023539; OTTHUMP00000023540; OTTHUMP00000023541; OTTHUMP00000023542; OTTHUMP00000023543; OTTHUMP00000023544; OTTHUMP00000023545; OTTHUMP00000023546; OTTHUMP00000023549; histone deacetylase-like 1 |
Gene ID : | 55869 |
mRNA Refseq : | NM_001166418 |
Protein Refseq : | NP_001159890 |
MIM : | 300269 |
UniProt ID : | Q9BY41 |
Chromosome Location : | Xq13 |
Function : | NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); histone deacetylase activity (H3-K16 specific); hydrolase activity; transcription factor binding; metal ion binding; histone deacetylase activity |
Products Types
◆ Recombinant Protein | ||
HDAC8-2473R | Recombinant Rat HDAC8 Protein, His (Fc)-Avi-tagged | +Inquiry |
HDAC8-125H | Recombinant Human HDAC8 Protein, His-tagged | +Inquiry |
HDAC8-314H | Active Recombinant Human HDAC8 Protein | +Inquiry |
HDAC8-26H | Recombinant Human HDAC8 Protein, His-tagged | +Inquiry |
HDAC8-4650H | Recombinant Human HDAC8 Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
HDAC8-537MCL | Recombinant Mouse HDAC8 cell lysate | +Inquiry |
HDAC8-691HCL | Recombinant Human HDAC8 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-2253 | HDAC8 Activity Fluorometric Assay Kit | +Inquiry |
Kit-1744 | HDAC8 Fluorogenic Assay Kit | +Inquiry |
Kit-1961 | HDAC8 Inhibitor Screening Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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