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Recombinant Human K(Lysine) Acetyltransferase 8, GST-tagged

Cat.No. : KAT8-1602H
Product Overview : Recombinant human KAT8 (2-467; contains the catalytic domain) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
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  • Gene Information
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Cat. No. : KAT8-1602H
Description : KAT8 (MYST1) or MYST histone acetyltransferase 1 is a signaling protein that belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein which play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. MYST1 have a chromodomain that involved in protein-protein interactions and targeting transcriptional regulators to chromatin. MYST histone acetyltransferase 1 is also involved in ATM function.
Applications : Western Blot
Molecular Weight : 83 kDa
Expression System : Sf9 insect cells using baculovirus.
Species : Human
Form : Recombinant protein stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
Purity : > 80 %
Concentration : 0.1 ug/ul
Sequences : 2-467
Storage : Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Pathways : p53 pathway
Gene Name : KAT8 K(lysine) acetyltransferase 8 [ Homo sapiens ]
Official Symbol : KAT8
Synonyms : KAT8; MOF; hMOF; MYST1; FLJ14040; MYST histone acetyltransferase 1; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1; MYST-1; EC 2.3.1.48; histone acetyltransferase MYST1; ortholog of Drosophila males absent on the first (MOF); probable histone acetyltransferase MYST1
Gene ID : 84148
mRNA Refseq : NM_032188
Protein Refseq : NP_115564
MIM : 609912
UniProt ID : Q9H7Z6
Chromosome Location : 16p11.2
Function : acetyltransferase activity; histone acetyltransferase activity; metal ion binding; methylated histone residue binding; protein binding; transcription factor binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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