Recombinant Human Superoxide Dismutase 2, Mitochondrial, GST-tagged

• Cat.No.: SOD2-1636H
• Product Overview: Recombinant full-length human SOD2 was expressed in E. coli cells using an N-terminal GST tag.

Specification

• Cat. No.: SOD2-1636H
• Description: This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
• Applications: Western Blot
• Molecular Weight: 51 kDa
• Species: Human
• Form: Recombinant protein stored in 50 mM Tris-HCL, pH 7.5, 150 mM NaCl, 0.1 mM PMSF, 0.25 mM DTT, 10 mM gluthione, 0.1 mM EDTA, 25 % glycerol.
• Purity: > 90 %
• Concentration: 0.2 ug/ul
• Sequences: Full-length
• Storage: Store product at -70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Gene Information

• Gene Name: SOD2 superoxide dismutase 2, mitochondrial [ Homo sapiens ]
• Official Symbol: SOD2
• Synonyms: SOD2; superoxide dismutase 2, mitochondrial; IPO-B; MNSOD; MVCD6; Mn-SOD; indophenoloxidase B; Mn superoxide dismutase; mangano-superoxide dismutase; manganese-containing superoxide dismutase; EC 1.15.1.1; Superoxide dismutase [Mn], mitochondrial; OTTHUMP00000017530; OTTHUMP00000017531; manganese superoxide dismutase
• Gene ID: 6648
• mRNA Refseq: NM_000636
• Protein Refseq: NP_000627
• MIM: 147460
• UniProt ID: P04179
• Chromosome Location: 6q25.3
• Function: manganese ion binding; metal ion binding; oxidoreductase activity; oxygen binding; protein binding; superoxide dismutase activity