Recombinant Human TNNI1 protein, His-tagged
Cat.No. : | TNNI1-4836H |
Product Overview : | Recombinant Human TNNI1 fused with His tag at N-terminal was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Troponin1 is a member of the tropomyosin family and regulates the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Troponin1 is part of a complex with troponin T and troponin C in which Troponin1 acts as an inhibitory subunit that blocks actin-myosin interactions and thereby mediates striated muscle relaxation. Troponin1 is expressed in cardiac and skeletal muscle during early development but is restricted to slow-twitch skeletal muscle fibers in adults. The Troponin1 protein prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol. |
Molecular Mass : | ~24 kDa |
Purity : | >75% |
Applications : | Western Blot |
Stability : | 1year at - 70 centigrade from date of shipment |
Storage : | Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Concentration : | 0.2 μg/μl |
Gene Name : | TNNI1 troponin I type 1 (skeletal, slow) [ Homo sapiens ] |
Official Symbol : | TNNI1 |
Synonyms : | TNNI1; troponin I type 1 (skeletal, slow); troponin I, skeletal, slow; troponin I, slow skeletal muscle; troponin I, slow-twitch isoform; TNN1; SSTNI; DKFZp451O223; |
Gene ID : | 7135 |
mRNA Refseq : | NM_003281 |
Protein Refseq : | NP_003272 |
MIM : | 191042 |
UniProt ID : | P19237 |
Chromosome Location : | 1q31.3 |
Pathway : | Muscle contraction, organism-specific biosystem; Striated Muscle Contraction, organism-specific biosystem; Striated Muscle Contraction, organism-specific biosystem; |
Function : | actin binding; tropomyosin binding; |
Products Types
◆ Recombinant Protein | ||
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TNNI1-9495M | Recombinant Mouse TNNI1 Protein, His (Fc)-Avi-tagged | +Inquiry |
TNNI1-2257H | Recombinant Human TNNI1 Protein, DDK-tagged | +Inquiry |
TNNI1-5864R | Recombinant Rat TNNI1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
TNNI1-883HCL | Recombinant Human TNNI1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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