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Recombinant Human TNNI1 protein, His-tagged

Cat.No. : TNNI1-4836H
Product Overview : Recombinant Human TNNI1 fused with His tag at N-terminal was expressed in E. coli.
  • Specification
  • Gene Information
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Description : Troponin1 is a member of the tropomyosin family and regulates the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Troponin1 is part of a complex with troponin T and troponin C in which Troponin1 acts as an inhibitory subunit that blocks actin-myosin interactions and thereby mediates striated muscle relaxation. Troponin1 is expressed in cardiac and skeletal muscle during early development but is restricted to slow-twitch skeletal muscle fibers in adults. The Troponin1 protein prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes.
Source : E. coli
Species : Human
Tag : His
Form : 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol.
Molecular Mass : ~24 kDa
Purity : >75%
Applications : Western Blot
Stability : 1year at - 70 centigrade from date of shipment
Storage : Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Concentration : 0.2 μg/μl
Gene Name : TNNI1 troponin I type 1 (skeletal, slow) [ Homo sapiens ]
Official Symbol : TNNI1
Synonyms : TNNI1; troponin I type 1 (skeletal, slow); troponin I, skeletal, slow; troponin I, slow skeletal muscle; troponin I, slow-twitch isoform; TNN1; SSTNI; DKFZp451O223;
Gene ID : 7135
mRNA Refseq : NM_003281
Protein Refseq : NP_003272
MIM : 191042
UniProt ID : P19237
Chromosome Location : 1q31.3
Pathway : Muscle contraction, organism-specific biosystem; Striated Muscle Contraction, organism-specific biosystem; Striated Muscle Contraction, organism-specific biosystem;
Function : actin binding; tropomyosin binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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