Recombinant Human Unc-51-Like Kinase 3 (C. elegans), His-tagged
Cat.No. : | ULK3-1116H |
Product Overview : | Full-length recombinant human ULK3 was expressed by baculovirus in Sf9 insect cells using an N-terminal His tag. |
- Specification
- Gene Information
- Related Products
Cat. No. : | ULK3-1116H |
Description : | ULK3 or unc-51-like kinase 3 is a member of the serine/threonine kinase family that is involved in the SHH signaling pathway as a positive regulator of GLI proteins. ULK3 enhances endogenous and over-expressed GLI transcriptional activity in cultured cells and alters its subcellular localization. Furthermore, ULK3 phosphorylates GLI proteins in vitro. ULK3 is widely expressed and its expression is higher in a number of tissues where SHH signaling is known to be active, again suggesting that ULK3 is involved in the SHH pathway as a positive regulator of GLI proteins. |
Applications : | Kinase Assay; Western Blot |
Molecular Weight : | 51kDa |
Expression System : | Sf9 insect cells using baculovirus |
Species : | Human |
Form : | Recombinant protein stored in 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150 mM imidazole, 0.1 mM PMSF, 0.25 mM DTT, 25% glycerol. |
Specific Activity : | 230nmol/min/mg |
Purity : | >90% |
Concentration : | 0.1 ug/ul |
Sequences : | Full-length |
Storage : | Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. Product shipped on dry ice. |
Pathways : | Regulation of autophagy; mTOR signaling pathway |
Gene Name : | ULK3 unc-51-like kinase 3 (C. elegans) [ Homo sapiens ] |
Official Symbol : | UKL3 |
Synonyms : | ULK3; unc-51-like kinase 3 (C. elegans); FLJ90566; DKFZp434C131; serine/threonine-protein kinase ULK3; DKFZP434C131; EC 2.7.11.1; Unc-51-like kinase 3 |
Gene ID : | 25989 |
mRNA Refseq : | NM_001099436 |
Protein Refseq : | NP_001092906 |
MIM : | 613472 |
UniProt ID : | Q6PHR2 |
Chromosome Location : | 15q24.1 |
Function : | ATP binding; nucleotide binding; protein binding; protein serine/threonine kinase activity |
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◆ Lysates | ||
ULK3-1883HCL | Recombinant Human ULK3 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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