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Recombinant Human Twinfilin, Actin-Binding Protein, Homolog 1 (Drosophila), His-tagged

Cat.No. : TWF1-1322H
Product Overview : Recombinant human TWF1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
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  • Gene Information
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Cat. No. : TWF1-1322H
Description : TWF1 is a ubiquitous actin-monomer-binding protein that is composed of two ADF-homology domains. It forms a 1:1 complex with ADP-actin-monomers, inhibits nucleotide exchange on actin monomers and prevents assembly of the monomer into filaments.
Form : Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT, 40% glycerol, 0.15 M NaCl.
Molecular Weight : 31.5 kDa (277 aa) confirmed by MALDI-TOF
Purity : > 80 % by SDS-PAGE
Concentration : 0.25 mg/ml (determined by Bradford assay)
Sequences of amino acids : MGSSHHHHHH SSGLVPRGSH MGSHMMLYAA TRATLKKEFG GGHIKDEVFG TVKEDVSLHG YKKYLLSQSS PAPLTAAEEE LRQIKINEVQ TDVGVDTKHQ TLQGVAFPIS REAFQALEKL NNRQLNYVQL EIDIKNEIII LANTTNTELK DLPKRIPKDS ARYHFFLYKH SHEGDYLESI VFIYSMPGYT CSIRERMLYS SCKSRLLEIV ERQLQMDVIR KIEIDNGDEL TADFLYEEVH PKQHAHKQSF AKPKGPAGKR GIRRLIRGPA ETEATTD
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Pathways : superpathway of gluconate degradation
Gene Name : TWF1 twinfilin, actin-binding protein, homolog 1 (Drosophila) [ Homo sapiens ]
Official Symbol : TWF1
Synonyms : TWF1; twinfilin, actin-binding protein, homolog 1 (Drosophila); A6; PTK9; MGC23788; MGC41876; twinfilin-1; protein A6; protein tyrosine kinase 9; A6 protein tyrosine kinase; PTK9 protein tyrosine kinase 9
Gene ID : 5756
mRNA Refseq : NM_001242397
Protein Refseq : NP_001229326
MIM : 610932
UniProt ID : Q12792
Chromosome Location : 12q12
Function : ATP binding; actin monomer binding; phosphatidylinositol-4,5-bisphosphate binding; protein tyrosine kinase activity; NOT protein tyrosine kinase activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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