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Recombinant Human Muscle RAS Oncogene Homolog, His-tagged

Cat.No. : MRAS-1335H
Product Overview : Recombinant human MRAS protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
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Cat. No. : MRAS-1335H
Description : MRAS (Ras-related protein M-Ras) belongs to the RAS superfamily. These families are membrane-anchored, intracellular signal transducers responsible for a variety of normal cellular functions. They are oncogenically activated in a significant fraction of tumors. MRAS serve as an important signal transducer for novel upstream stimuli in controlling cell proliferation.
Form : Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 5 mM DTT, 40% glycerol, 200 mM NaCl, 2 mM EDTA.
Molecular Weight : 25.7 kDa (225 aa), confirmed by MALDI-TOF
Purity : > 90 % by SDS-PAGE
Concentration : 0.5 mg/ml (determined by Bradford assay)
Sequences of amino acids : MGSSHHHHHH SSGLVPRGSH MATSAVPSDN LPTYKLVVVG DGGVGKSALT IQFFQKIFVP DYDPTIEDSY LKHTEIDNQW AILDVLDTAG QEEFSAMREQ YMRTGDGFLI VYSVTDKASF EHVDRFHQLI LRVKDRESFP MILVANKVDL MHLRKITREQ GKEMATKHNI PYIETSAKDP PLNVDKAFHD LVRVIRQQIP EKSQKKKKKT KWRGDRATGT HKLQC
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Pathways : HTLV-I infection; IL-3 Signaling Pathway; MAPK signaling pathway; Regulation of Actin Cytoskeleton; Tight junction
Gene Name : MRAS muscle RAS oncogene homolog [ Homo sapiens ]
Official Symbol : MRAS
Synonyms : MRAS; muscle RAS oncogene homolog; M-RAs; RRAS3; R-RAS3; FLJ42964; ras-related protein M-Ras; OTTHUMP00000216882; OTTHUMP00000216883; OTTHUMP00000216886; OTTHUMP00000216887; muscle and microspikes RAS; ras-related protein R-Ras3
Gene ID : 22808
mRNA Refseq : NM_001085049
Protein Refseq : NP_001078518
MIM : 608435
UniProt ID : O14807
Chromosome Location : 3q22.3
Function : GTP binding; GTP-dependent protein binding; GTPase activity; nucleotide binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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