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Human Transferrin

Cat.No. : TF-4778H
Product Overview : This product is excellent for use as a growth factor for primary, continuous, and transformed cell lines.
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  • Gene Information
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Cat. No. : TF-4778H
Description : TF is a glycoprotein that binds iron very tightly but reversibly. Although iron bound to transferrin is less than 0.1% (4 mg) of the total body iron, it is the most important iron pool, with the highest rate of turnover (25 mg/24 h). TF has a molecular weight of around 80 kDa and contains 2 specific high-affinity Fe (III) binding sites.
Source : Human Plasma
Species : Human
Source Testing : The normal human serum/plasma of each donor unit, from which this product was manufactured, has been tested and certified negative for the following by FDA approved testing procedures: HBsAg, Anti-HCV, Anti-HIV-1, Anti-HIV-2, Syphilis, ALT Test and NAT-PCR ( HAV, HIV, HBC, HCV and Parovirus B19). Human blood products should always be treated in accordance with universal handling precautions.
Protein : 97.0% By Lowry.
Purity : > 98% By Cellulose Acetate Electrophoresis.
Iron : 1500 µg/g By Diagnostic Assay.
pH : 7.06 (3% Solution)
Endotoxin : < 0.076 EU/mg By LAL.
Sodium : 0.0-10.0 mg/g By Flame Photometer.
Chloride : 0.0-12.0 mg/g By Coulometric Titrator.
Moisture : 0.87% By Karl Fisher.
Storage : Store at -20°C.
Pathways : EPHB forward signaling; Formation of Platelet plug; HIF-1-alpha transcription factor network; Hemostasis; Iron uptake and transport; Mineral absorption; Platelet Activation; Platelet degranulation; Response to elevated platelet cytosolic Ca2+; Transferrin endocytosis and recycling; Transmembrane transport of small molecules
Gene Name : TF transferrin [ Homo sapiens ]
Official Symbol : TF
Synonyms : TF; transferring; PRO1557; PRO2086; DKFZp781D0156; serotransferrin; siderophilin; OTTHUMP00000197155; beta-1 metal-binding globulin; Serotransferrin; Beta-1 metal-binding globulin; Siderophilin
Gene ID : 7018
mRNA Refseq : NM_001063
Protein Refseq : NP_001054
MIM : 190000
UniProt ID : P02787
Chromosome Location : 3q21
Function : ferric iron binding; metal ion binding; protein binding; ubiquitin protein ligase binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can TF proteins be used for diagnosing diseases? 03/19/2021

Yes, abnormalities in TF proteins can serve as diagnostic markers for certain diseases.

Are there any approved drugs that target TF proteins? 11/27/2020

Yes, some drugs target TF proteins, especially in the treatment of cancer.

How do TF proteins contribute to autoimmune diseases? 08/25/2020

TF proteins can trigger or suppress immune responses, making them relevant in understanding autoimmune diseases.

How do TF proteins play a crucial role in clinical applications? 03/16/2016

TF proteins are vital for understanding disease mechanisms and can be targeted for therapeutic purposes.

Are there any clinical tests or assays that measure TF protein levels? 03/05/2016

Yes, various assays, like ELISA and Western blot, can be used to quantify TF protein levels.

Customer Reviews (3)

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Reviews
08/01/2020

    Their team of experts is not only knowledgeable about the TF protein but is also dedicated to assisting researchers like myself in overcoming any challenges that may arise.

    01/22/2018

      This high-quality protein is crucial for the success of my experiments, ensuring that I obtain reliable and meaningful scientific findings.

      04/11/2016

        The TF protein is of exceptional quality, making it a perfect fit for my experimental needs.

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