Active Recombinant Human Insulin-Like Growth Factor Binding Protein 2, 36kDa
Cat.No. : | IGFBP2-5049H |
Product Overview : | Recombinant Human IGFBP2 was expressed in Hi-5 Insect cells and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Cat. No. : | IGFBP2-5049H |
Description : | IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP2 is a cysteine-rich secreted protein produced by bone cells, and is most abundant in the brain. IGF-BP2 has been shown to inhibit IGF-II action in human breast and ovarian carcinoma cells. |
Source : | Human |
Host : | Hi-5 Insect cells |
Form : | Supplied as a lyophilized powder. |
Purity : | >98% pure by SDS PAGE and HPLC |
Sequence : | Region of IGF BP2 protein corresponding to amino acids EVLFRCPPCT PERLAACGPP PVAPPAAVAA VAGGARMPCA ELVREPGCGC CSVCARLEGE ACQVYTPRCG QGLRCYPHPG SELPLQALVM GEGTCEKRRD AEYGASPEQV ADNGDDHSEG GLVENHVDST MNMLGGGGSA GRKPLKSGMK ELAVFREKVT EQHRQMGKGG KHHLGLEEPK KL |
Molecular Mass : | 31.5 kDa |
Applications : | Numerous applications are possible with this product and should be tested by the end user under their own laboratory conditions |
Endotoxin Levels : | Endotoxin level is less than 0.1 ng per ug (1 EU/ug). |
Bioactivity : | Determined by its ability to inhibit IGF-I induced proliferation of FDC-P1 cells. |
Storage : | Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
Gene Name : | IGFBP2 insulin-like growth factor binding protein 2, 36kDa [ Homo sapiens ] |
Official Symbol : | IGFBP2 |
Synonyms : | insulin-like growth factor binding protein 2, 36kDa; IBP2; IGF-BP53; IGFBP2; BP2; IBP-2; IGFBP-2; IGF-binding protein 2; insulin-like growth factor binding protein 2 (36kD); OTTHUMP00000207751; OTTHUMP00000207753 |
Gene ID : | 3485 |
mRNA Refseq : | NM_000597 |
Protein Refseq : | NP_000588 |
MIM : | 146731 |
UniProt ID : | P18065 |
Chromosome Location : | 2q33-q34 |
Pathway : | Diabetes pathways; Myometrial Relaxation and Contraction Pathways; Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
Function : | insulin-like growth factor I binding; insulin-like growth factor II binding; protein binding |
Products Types
◆ Recombinant Protein | ||
IGFBP2-991H | Recombinant Human IGFBP2 Protein, His-tagged | +Inquiry |
IGFBP2-132H | Recombinant Human IGFBP2 Protein, His-tagged(C-ter) | +Inquiry |
IGFBP2-993C | Recombinant Cattle IGFBP2 Protein, His-tagged | +Inquiry |
Igfbp2-990M | Recombinant Mouse Igfbp2 Protein, His-tagged | +Inquiry |
IGFBP2-02H | Recombinant Human IGFBP2 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
IGFBP2-1457CCL | Recombinant Cynomolgus IGFBP2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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