Active Recombinant Human ERBB3 Protein

• Cat.No.: ERBB3-23H
• Product Overview: Recombinant human ERBB3 protein produced in E.coli is a single, non-glycosylated polypeptide consisting of several epitopes of extracellular domain of human Erb-b3.

Specification

• Source: E.coli
• Species: Human
• Bio-activity: Measured by its ability to postpone tumor emerge time of spontaneous breast cancer in FVB/N transgenic mice and inhibit the development of tumor, effectively inhibit the growth of in situ transplanted breast cancer in FVB/N transgenic mice.
• Molecular Mass: 12.0 kDa
• Purity: Greater than 95.0% as determined by:
  (a) Analysis by RP-HPLC.
  (b) Analysis by SDS-PAGE.
• Stability: ErbB3 although stable at 4 centigrade for 1 week, should be stored below -18 centigrade.
  For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
  Please prevent freeze-thaw cycles.
• Concentration: 1 mg/mL
• Storage Buffer: Each mg protein contains 1 mg aluminum hydroxide 10 mM arginine, 10 mM sodium chloride, 20 mM sodium phosphate buffer and 5 mM potassium phosphate.
• Dilutions: It is recommended that sterile phosphate-buffered saline containing 1 mg aluminum hydroxide be added to the vial to prepare a stock solution.
• Shipping: Shipped with ice packs.

Gene Information

• Gene Name: ERBB3 erb-b2 receptor tyrosine kinase 3 [ Homo sapiens (human) ]
• Official Symbol: ERBB3
• Synonyms: ERBB3; erb-b2 receptor tyrosine kinase 3; HER3; FERLK; LCCS2; ErbB-3; c-erbB3; erbB3-S; MDA-BF-1; c-erbB-3; p180-ErbB3; p45-sErbB3; p85-sErbB3; receptor tyrosine-protein kinase erbB-3; human epidermal growth factor receptor 3; proto-oncogene-like protein
• Gene ID: 2065
• mRNA Refseq: NM_001982
• Protein Refseq: NP_001973
• MIM: 190151
• UniProt ID: P21860