Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Human Heat Shock Protein 90kDa Beta (Grp94), Member 1

Cat.No. : HSP90B1-07H
  • Specification
  • Gene Information
  • Related Products
Cat. No. : HSP90B1-07H
Product overview : Recombinant Human heat shock protein 90β produced in E. coli has a molecular mass of approximately 85 KDa.
Description : An approximately 90 kDa heat shock protein constitutively expressed in the cytoplasm. It exists as a dimer and has been observed to bind other cellular proteins such as p60v-src, steroid receptors, heme-regulated protein kinase, actin, and tubulin. Bind to histones with high affinity and induces chromatin condensation.
Source : E. coli.
Purity : >95% as determined by SDS-PAGE.
Specific Activity : The biological activity ofHSP90B1 is measured by its ability to support survival and stimulate neurite outgrowth of cultured embryonic chick dorsal root ganglia. Activity can also be measured by its ability to bind recombinant human GFRα1/Fc.
Storage Buffer : Liquid. In PBS Buffer. Avoid freeze/thaw cycles.
Gene Name : HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 [ Homo sapiens ]
Synonyms : ECGP; GP96; GRP94; TRA1;94 kDa glucose-regulated protein; Endoplasmin precursor; Heat shock protein 90 kDa beta member 1; Tumor rejection antigen 1; Tumor rejection antigen-1 (gp96); endothelial cell (HBMEC) glycoprotein; glucose regulated protein; 94 kDa; gp96 homolog; heat shock protein 90kDa beta (Grp94), member 1; tumor rejection antigen (gp96) 1
Gene ID : 7184
mRNA Refseq : NM_003299
Protein Refseq : NP_003290
MIM : 191175
Uniprot ID : O95433
Chromosome Location : 12q24.2-q24.3
Pathway : Pathways in cancer; Prostate cancer
Function : ATP binding, RNA binding, calcium ion binding, low-density lipoprotein receptor binding, nucleotide binding, unfold protein binding, virion binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (5)

Ask a question
How does HSP90B1 interact with other cellular components in the endoplasmic reticulum? 10/04/2022

HSP90B1 interacts with various proteins and participates in complex cellular processes, including protein folding, quality control, and antigen presentation.

Are there any ongoing clinical trials targeting HSP90B1 for therapeutic purposes? 07/03/2020

It's possible. You may want to check the latest clinical trial databases for the most up-to-date information.

Does the expression of HSP90B1 vary in different tissues of the human body? 10/21/2018

Yes, the expression of HSP90B1 can vary among tissues, reflecting its diverse functions in different cellular environments.

Can HSP90B1 be used as a diagnostic marker for certain diseases? 08/25/2017

Research suggests that HSP90B1 levels may be altered in some diseases, making it a potential diagnostic marker, but more studies are needed for validation.

Can genetic mutations in HSP90B1 lead to diseases? 06/14/2016

Mutations in HSP90B1 have been associated with certain diseases, highlighting the importance of its proper function for cellular health.

Customer Reviews (3)

Write a review
Reviews
05/03/2022

    Their in-depth understanding of the protein's characteristics, applications, and potential limitations allows for valuable insights and recommendations, ensuring the success of my experiments.

    12/22/2018

      Whether it's troubleshooting, protocol optimization, or general inquiries, their knowledgeable and responsive team is readily available to assist and solve any problems that may arise during the experimental process.

      12/15/2018

        Its purity, integrity, and consistency ensure reliable and reproducible results, which are essential for meaningful scientific discoveries.

        Ask a Question for All HSP90B1 Products

        Required fields are marked with *

        My Review for All HSP90B1 Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends