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Recombinant Human SUM02

Cat.No. : SUM02-13H
Product Overview : Recombinant Human SUMO2 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 95 amino acids and having a molecular mass of 11 kDa. The SUMO-2 is purified by proprietary chromatographic techniques.
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  • Gene Information
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Cat. No. : SUM02-13H
Description : Small Ubiquitin-like Modifiers (SUMOs) are a family of small, related proteins that can be enzymatically attached to a target protein by a post-translational modification process termed sumoylation. Unlike ubiquitination, which targets proteins for degradation, sumoylation participates in a number of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. All SUMO proteins share the conserved ubiquitin domain and the C-terminal diglycine cleavage/attachment site. Human SUMO2, also known as Sentrin2 and SMT3B is synthesized as a 95 amino acid (aa), 11 kDa propeptide that contains a two aa C-terminal prosegment, and an 18 aa N-terminal protein interacting region (aa 33 -50). Following prosegment cleavage, the C-terminal glycine is enzymatically attached to a lysine on a target protein. Human SUMO2 shares 100% sequence identity to SUMO-2 from mouse. SUMO2 also has very high sequence homology to SUMO3 and SUMO4, 86 % and 85%, respectively. SUMO2 shares only 44% sequence identity to SUMO1.
Source : Escherichia Coli.
Physical Appearance : Sterile Filtered White lyophilized (freeze-dried) powder.
Purity : Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Formulation : The SUMO2 was lyophiized from 1X PBS, pH 7.4.
Stability : Lyophilized SUMO2 although stable 10°C for 1 week, should be stored desiccated below -18°C. Please prevent freeze-thaw cycles.
Gene Name : SUMO2 SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae) [ Homo sapiens ]
Synonyms : SUMO-2; Ubiquitin-like protein SMT3B, SMT3 homolog 2; Sentrin-2; HSMT3; SUMO-3; Sentrin2; SUMO2; SMT3H2; MGC117191; SMT3 suppressor of mif two 3 homolog 2; sentrin 2; small ubiquitin-like modifier 2, isoform a, SMT3B; SUMO-3; SMT3 (suppressor of mif two 3, yeast) homolog 2; SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae); SMT3 suppressor of mif two 3 homolog 2 (yeast); Ubiquitin-like protein SMT3B; sentrin 2.
Gene ID : 6613
mRNA Refseq : NM_001005849
Protein Refseq : NP_001005849
MIM : 603042
UniProt ID : P61956
Chromosome Location : 17q25.1
Function : protein binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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