Recombinant Human CD4 Molecule, His-tagged (125-202aa)
Cat.No. : | CD4-101H |
Product Overview : | Recombinant Human CD-4 is expressed in E. coli encoding 125-202 amino acids, having a total molecular weight of 15kDa and fused to an amino terminal hexahistidine tag. |
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Cat. No. : | CD4-101H |
Description : | CD4, a single chain transmembrane glycoprotein, is found on a T cell subset (helper/inducer) representing 45% of peripheral blood lymphocytes. It is also present on 80% of thymocytes and at a lower level on monocytes. It is involved in recognition of antigen presented along with MHC class II by APCs. It serves as receptor for HIV. Antibody to CD4 recognizes T-helper cells required for recognition of class II antigens. It reacts with ~60% of peripheral blood E rosette-positive (E+) cells while showing negligible reactivity with E-cells, monocytes, granulocytes, EBV-transformed B cell lines, and mouse splenocytes. |
Source : | Escherichia Coli. |
Physical Appearance : | Sterile lyophilized powder. |
Purity : | Greater than 90% determined by SDS-PAGE. |
Formulation : | Each mg contains 1X PBS. |
Solubility : | It is recommended to reconstitute the lyophilized CD-4 (125-202) in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. |
Application : | • Protein Assay • Antibody Production • Western Blotting |
Storage : | Store vial at -20°Cto -80°C. When stored at the recommended temperature, this protein is stable for 12months. Please avoid freeze-thaw cycles. |
Gene Name : | CD4 CD4 molecule [ Homo sapiens ] |
Synonyms : | CD4; CD4 molecule; CD4mut; T-cell surface glycoprotein CD4; CD4 antigen (p55); T-cell surface antigen T4/Leu-3; CD_antigen; CD4 antigen; CD4 receptor |
Gene ID : | 920 |
mRNA Refseq : | NM_000616 |
Protein Refseq : | NP_000607 |
MIM : | 186940 |
UniProt ID : | P01730 |
Chromosome Location : | 12pter-p12 |
Pathway : | Antigen processing and presentation; Cell adhesion molecules (CAMs); Hematopoietic cell lineage; Primary immunodeficiency; T cell receptor signaling pathway; HIV Infection; Signaling in Immune system |
Function : | MHC class II protein binding; coreceptor activity; extracellular matrix structural constituent; protein homodimerization activity; protein kinase binding; transmembrane receptor activity; zinc ion binding |
Products Types
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CD4-565R | Recombinant Rhesus Macaque CD4 Protein, His (Fc)-Avi-tagged | +Inquiry |
CD4-0809M | Recombinant Monkey CD4 Protein, His-Tagged | +Inquiry |
◆ Lysates | ||
CD4-2580MCL | Recombinant Mouse CD4 cell lysate | +Inquiry |
CD4-1905HCL | Recombinant Human CD4 cell lysate | +Inquiry |
CD4-947CCL | Recombinant Cynomolgus CD4 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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