Recombinant Human AHSG protein, His-tagged
Cat.No. : | AHSG-7710H |
Product Overview : | Recombinant Human AHSG (Ala19-Val367) protein was fused to His-tag at C-terminus and expressed in human 293 cells (HEK293). |
- Specification
- Gene Information
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Description : | Alpha-2-HS-glycoprotein (AHSG) is also known as Alpha-2-Z-globulin, Ba-alpha-2-glycoprotein, Fetuin-A (FETUA), is a glycoprotein that is composed of two subunits, the A and B chains, belongs to the cystatin family of proteases inhibitors and the fetuin class of plasma binding proteins. AHSG/Fetuin A is highly expressed in embryonic cells and adult hepatocytes, and is expressed to a lesser extent in monocytes/macrophages. Fetuins are carrier proteins like albumin. Fetuin-A/AHSG forms soluble complexes with calcium and phosphate and thus is a carrier of otherwise insoluble calcium phosphate. Thus AHSG/Fetuin A is a potent inhibitor of pathological calcification. Fetuin A/FETUA promotes phagocytosis of apoptotic cells and plays a role in bone development, calcium homeostasis and insulin sensitivity. Mice deficient in Fetuin-A show systemic calcification of soft tissues. |
Source : | HEK293 |
Species : | Human |
Tag : | His |
Predicted N Terminal : | Ala19 |
Form : | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 38.2 kDa. The protein migrates as 55-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein length : | Ala19-Val367 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >98% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | AHSG |
Official Symbol : | AHSG |
Synonyms : | AHSG; alpha-2-HS-glycoprotein; A2HS; FETUA; HSGA; fetuin-A; alpha-2-Z-globulin; ba-alpha-2-glycoprotein; AHS |
Gene ID : | 197 |
mRNA Refseq : | NM_001622 |
Protein Refseq : | NP_001613 |
MIM : | 138680 |
UniProt ID : | P02765 |
Products Types
◆ Recombinant Protein | ||
AHSG-103P | Recombinant Pig AHSG Protein, His-tagged | +Inquiry |
Ahsg-557M | Recombinant Mouse Ahsg Protein, MYC/DDK-tagged | +Inquiry |
AHSG-816H | Recombinant Human AHSG Protein | +Inquiry |
Ahsg-408M | Recombinant Mouse Ahsg Protein, His (Fc)-Avi-tagged | +Inquiry |
AHSG-101C | Recombinant Cattle AHSG Protein, His-tagged | +Inquiry |
◆ Native Protein | ||
AHSG-111H | Native Human Alpha 2 HS Glycoprotein | +Inquiry |
AHSG-1001H | Human Leucine-rich Alpha-2-glycoprotein 1 | +Inquiry |
◆ Lysates | ||
AHSG-2958HCL | Recombinant Human AHSG cell lysate | +Inquiry |
AHSG-2957MCL | Recombinant Mouse AHSG cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionTechniques like co-immunoprecipitation coupled with mass spectrometry can reveal AHSG's interactome, shedding light on its broader functional networks.
AHSG levels may be altered in these conditions, making it a potential biomarker for disease progression or severity.
AHSG's interaction with insulin and adipokines could impact insulin sensitivity and metabolism, contributing to insulin resistance in conditions like type 2 diabetes.
AHSG can form complexes with fetuin-B and fetuin-A, which have implications for calcium homeostasis, insulin signaling, and other physiological processes.
AHSG can interact with immune cells and cytokines, potentially influencing immune responses. Dysregulated AHSG levels might contribute to autoimmune diseases.
AHSG's interactions with proteins like albumin and hormones can impact its bioavailability and activity, influencing physiological processes.
Techniques such as mass spectrometry, lectin affinity chromatography, and glycan analysis can provide insights into AHSG's glycosylation patterns.
AHSG binds to calcium ions and influences their distribution in the body. Dysregulation may impact bone health and contribute to conditions like osteoporosis.
Techniques such as ion exchange chromatography, gel filtration, and affinity chromatography can be used to isolate and purify AHSG from biological samples.
Genetic polymorphisms in the AHSG gene might lead to altered AHSG levels or structural changes, potentially influencing its physiological roles.
Customer Reviews (5)
Write a reviewAbsolutely loving the lab protein – a real game changer!
Great value for the quality, and the speedy delivery was a pleasant surprise!
Thumbs up for the protein, it's become my new favorite.
Can't help but smile at the results from the product!
Balanced pricing, superior quality, and top-level customer assistance.
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