Native Human Serum Alpha 1-AntiChymoTrypsin
Cat.No. : | SERPINA3-8008H |
Product Overview : | Human Serum Alpha 1-AntiChymoTrypsin was purified from Human Serum. |
- Specification
- Gene Information
- Related Products
Description : | Human Alpha 1 antichymotrypsin (Alpha 1-ACT) (ACT)is an alpha globulin glycoprotein and serpin. This Human Glycoprotein is found in alpha(1)-globulin region in human serum. Human Alpha 1-antichymotrypsin (ACT)(Alpha 1-ACT) inhibits chymotrypsin-like proteinases in vivo and has cytotoxic killer-cell activity in vitro. Human Alpha 1-antichymotrypsin (ACT)(Alpha 1-ACT) also has a role as an acute-phase protein and is active in the control of immunologic and inflammatory processes, and as a tumor marker. Human Alpha 1-antichymotrypsin (ACT)(Alpha 1-ACT) is a member of the serpin superfamilyHuman Alpha 1-antichymotrypsin (Alpha 1-ACT) (ACT)can complex with human PSA to form human PSA-ACT complex which is used as an indicator of tumour mass and clinical stage of prostate cancer |
Source : | Human Serum |
Species : | Human |
Form : | Lyophilized from 0.02M Tris buffer, pH 7.5 containing 0.15M NaCl |
Molecular Mass : | 68 kDa |
Purity : | >90% by SDS-PAGE |
Stability : | 2 years |
Storage : | 2-8 °C |
Gene Name : | SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 [ Homo sapiens ] |
Official Symbol : | SERPINA3 |
Synonyms : | SERPINA3; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3; AACT, alpha 1 antichymotrypsin , serine (or cysteine) proteinase inhibitor, clade A (alpha 1 antiproteinase, antitrypsin), member 3; alpha-1-antichymotrypsin; |
Gene ID : | 12 |
mRNA Refseq : | NM_001085 |
Protein Refseq : | NP_001076 |
MIM : | 107280 |
UniProt ID : | P01011 |
Chromosome Location : | 14q32.1 |
Pathway : | Selenium Pathway, organism-specific biosystem; |
Function : | DNA binding; peptidase inhibitor activity; protein binding; serine-type endopeptidase inhibitor activity; serine-type endopeptidase inhibitor activity; |
Products Types
◆ Recombinant Protein | ||
SERPINA3-571H | Recombinant Human SERPINA3 Protein, His-tagged | +Inquiry |
SERPINA3-2H | Recombinant Horse SERPINA3 Protein, His (Fc)-Avi-tagged | +Inquiry |
SERPINA3-3238H | Recombinant Human SERPINA3 protein, His-tagged | +Inquiry |
SERPINA3-3758H | Recombinant Human SERPINA3 protein, His-tagged | +Inquiry |
SERPINA3-2700H | Active Recombinant Human SERPINA3 protein, His-tagged | +Inquiry |
◆ Native Protein | ||
SERPINA3-27285TH | Native Human SERPINA3 | +Inquiry |
SERPINA3-8349H | Native Human SERPINA3 | +Inquiry |
SERPINA3-5331H | Native Human Serpin Peptidase Inhibitor, Clade A (alpha-1 antiproteinase, antitrypsin), Member 3 | +Inquiry |
◆ Lysates | ||
SERPINA3-2522HCL | Recombinant Human SERPINA3 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (7)
Ask a questionSerpina3n plays significant roles in various physiological processes, including modulation of the complement cascade, apoptosis, wound healing, and potential implications in Alzheimer's disease.
Recent studies have reported significant roles of Serpina3n during various pathologies, particularly in central nervous system (CNS) insults, making it a potential therapeutic target.
The aim is to compile literature shedding light on the potential therapeutic applications of Serpina3n/SERPINA3 in various diseases. Additionally, a brief comparison between murine Serpina3n and its human ortholog SERPINA3 (α1-antichymotrypsin) is provided to account for their biological roles and significance.
The full range of potential applications of Serpina3n is yet to be fully revealed, but its reported implications, especially in CNS insults, suggest potential therapeutic applications.
Serpina3n is a secretory serine protease inhibitor belonging to clade "a" with unique structural and physiological characteristics. |
Serpina3n inhibits a wide range of proteases, contributing to its diverse physiological roles.
Serpina3n belongs to clade "a" of serine protease inhibitors. |
Customer Reviews (3)
Write a reviewThe product's impact extended to data analysis, with intuitive tools for interpreting experimental results.
The longevity of the product's effects allowed us to study cellular responses over extended timeframes.
We found that the product's support for data analysis and visualization significantly expedited our research.
Ask a Question for All SERPINA3 Products
Required fields are marked with *
My Review for All SERPINA3 Products
Required fields are marked with *
Inquiry Basket