Native Human Beta 2 MicroGlobulin
Cat.No. : | B2M-8046H |
Product Overview : | Human Beta 2 MicroGlobulin was purified from Human Urine. |
- Specification
- Gene Information
- Related Products
Description : | Serum beta-2 Microglobulin is an endogenous marker for renal function an has been shown to be an independent predictor of mortality in older adults. It has been reported that Serum B2M concentration is increased in renal diseases, various malignant diseases and some inflammatory and autoimmune disorders. |
Source : | Human Urine |
Species : | Human |
Form : | Phosphate Buffered Saline |
Molecular Mass : | 11.8 kDa |
Purity : | >98% by SDS-PAGE |
Storage : | 2-8 °C |
Concentration : | Typically >2.0 mg/mL |
Gene Name : | B2M beta-2-microglobulin [ Homo sapiens ] |
Official Symbol : | B2M |
Synonyms : | B2M; beta-2-microglobulin; beta-2-microglobin; beta chain of MHC class I molecules; |
Gene ID : | 567 |
mRNA Refseq : | NM_004048 |
Protein Refseq : | NP_004039 |
MIM : | 109700 |
UniProt ID : | P61769 |
Chromosome Location : | 15q21-q22.2 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Amyloids, organism-specific biosystem; Antigen Presentation: Folding, assembly and peptide loading of class I MHC, organism-specific biosystem; Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; Antigen processing-Cross presentation, organism-specific biosystem; Class I MHC mediated antigen processing and |
Function : | protein binding; |
Products Types
◆ Recombinant Protein | ||
B2M-414H | Recombinant Human B2M Protein, His (Fc)-Avi-tagged | +Inquiry |
B2M-103C | Recombinant Cynomolgus monkey B2M Protein, His-tagged | +Inquiry |
B2M-105R | Recombinant Rat B2M Protein, His and Strep-tagged | +Inquiry |
B2M-104H | Recombinant Human B2M Protein, His-tagged | +Inquiry |
B2M-2208H | Recombinant Human B2M Protein, MYC/DDK-tagged | +Inquiry |
◆ Native Protein | ||
B2M-13H | Native Human B2M | +Inquiry |
B2M-5366H | Native Human Beta-2-Microglobulin | +Inquiry |
◆ Lysates | ||
B2M-1550RCL | Recombinant Rat B2M cell lysate | +Inquiry |
B2M-2204HCL | Recombinant Human B2M cell lysate | +Inquiry |
B2M-1512CCL | Recombinant Cynomolgus B2M cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionThe normal reference range for B2M varies depending on age, gender, weight, individual differences, and other factors. In general, the normal reference range is between 0~3.0mg/L.
Causes of reduced B2M include liver and kidney failure, tuberculosis, HIV infection, rheumatoid arthritis, systemic lupus erythematosus and other diseases.
B2M plays an important role in the diagnosis and prognosis assessment of malignancies such as lymphoma and multiple myeloma. Elevated B2M levels can also indicate worsening or recurrence of certain autoimmune diseases, such as systemic lupus erythematosus.
It has a variety of physiological functions in the immune system, including inducing immune response, participating in lymphocyte proliferation and differentiation, regulating immune tolerance, and participating in tumor immune surveillance.
The levels can be affected by a variety of factors, such as cancer, inflammation, autoimmune diseases, infections, medications, etc.
This is associated with many diseases, including lymphoma, normal stress hydrocephalus, HIV infection, rheumatoid arthritis, nephrotic syndrome, cirrhosis, systemic lupus erythematosus, etc.
Customer Reviews (3)
Write a reviewTo meet the needs of biological activity experiments
High purity, no impurities.
The expression level is high, which can meet the daily experimental needs.
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