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Native Human CKB protein

Cat.No.: CKB-8079H
Product Overview: Native Human CKB was purified in Human Brain.
Description: The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in brain as well as in other tissues, and as a heterodimer with a similar muscle isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. A pseudogene of this gene has been characterized.
Source: Human Brain
Species: Human
Form: 50% Glycerol, 25 mM Imidazole, 1 mM DTE, pH 6.5.
Bio-activity: > 500 U/mL (Dimension® Clinical Chemistry System)
Unit Definition: One unit will transfer one micromole of phosphate from creatine phosphate to ADP per minute at 37 centigrade
Storage: Store at -20 centigrade.
Concentration: > 0.5 mg protein/mL (Coomassie)
Gene Name: CKB creatine kinase, brain [ Homo sapiens ]
Official Symbol: CKB
Synonyms: CKB; creatine kinase, brain; CKBB; creatine kinase B-type; creatine kinase-B; creatine kinase B chain; B-CK;
Gene ID: 1152
mRNA Refseq: NM_001823
Protein Refseq: NP_001814
MIM: 123280
UniProt ID: P12277
Chromosome Location: 14q32.32
Pathway: Arginine and proline metabolism, organism-specific biosystem; Arginine and proline metabolism, conserved biosystem; Creatine metabolism, organism-specific biosystem; Creatine pathway, organism-specific biosystem; Creatine pathway, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem;
Function: ATP binding; creatine kinase activity; nucleotide binding;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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