Recombinant Human VEGFC

• Cat.No.: VEGFC-8329H
• Product Overview: Recombinant Human VEGFC was expressed in HEK 293 cells.

Specification

• Description: Vascular endothelial growth factor C (VEGF-C) is a member of the VEGF family and is known to be associated with angiogenesis and lymphangiogenesis in various cancers.?VEGF-C plays a key role in the physiology and pathology of many aspects of the cardiovascular system, including vasculogenesis, hematopoiesis, angiogenesis and vascular permeability.?VEGF-C may participate in the development and progression of angiogenic diseases.
• Source: HEK 293 cells
• Species: Human
• Form: The protein was 0.2 μm filtered and lyophilized from PBS.
• Molecular Mass: The predicted molecular weight of Recombinant Human VEGF-C is Mr 15.4 kDa. However, the actual molecular weight as observed by migration on SDS-PAGE is Mr 23 kDa.
• AA Sequence: MAHYNTEILK SIDNEWRKTQ CMPREVCIDV GKEFGVATNT FFKPPCVSVY RCGGCCNSEG LQCMNTSTSY LSKTLFEITV PLSQGPKPVT ISFANHTSCR CMSKLDVYRQ VHSIIRR
• Endotoxin: <1.0 eu/μg as determined by the lal>
• Purity: >95% by SDS-PAGE and analyzed by silver stain.
• Storage: This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.

Gene Information

• Gene Name: VEGFC vascular endothelial growth factor C [ Homo sapiens ]
• Official Symbol: VEGFC
• Synonyms: VEGFC; vascular endothelial growth factor C; VRP; VEGF-C; FLT4 ligand DHM; vascular endothelial growth factor-related protein; Flt4-L
• Gene ID: 7424
• mRNA Refseq: NM_005429
• Protein Refseq: NP_005420
• MIM: 601528
• UniProt ID: P49767
• Chromosome Location: 4q34.3
• Pathway: Bladder cancer, organism-specific biosystem; Bladder cancer, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Focal Adhesion, organism-specific biosystem; Focal adhesion, organism-specific biosystem; Focal adhesion, conserved biosystem
• Function: chemoattractant activity; growth factor activity; protein binding; vascular endothelial growth factor receptor 3 binding