Native Human PGC
Cat.No. : | PGC-8318H |
Product Overview : | Pepsinogen II (Pepsinogen C) was purified from Human Gastric Mucosa. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. |
Source : | Human |
Species : | Human |
Form : | Not lyophilised. |
Purity : | Purified. |
Gene Name : | PGC progastricsin (pepsinogen C) [ Homo sapiens ] |
Official Symbol : | PGC |
Synonyms : | PGC; progastricsin (pepsinogen C); gastricsin; pepsin C; pepsinogen C; preprogastricsin; pepsinogen group II; PEPC; PGII; FLJ99563; |
Gene ID : | 5225 |
mRNA Refseq : | NM_001166424 |
Protein Refseq : | NP_001159896 |
MIM : | 169740 |
UniProt ID : | P20142 |
Chromosome Location : | 6p21.1 |
Function : | aspartic-type endopeptidase activity; peptidase activity; |
Products Types
◆ Recombinant Protein | ||
PGC-1315H | Recombinant Human PGC Protein, MYC/DDK-tagged | +Inquiry |
PGC-0041H | Recombinant Human PGC Protein | +Inquiry |
PGC-6662M | Recombinant Mouse PGC Protein, His (Fc)-Avi-tagged | +Inquiry |
Pgc-438M | Recombinant Mouse Pgc Protein, MYC/DDK-tagged | +Inquiry |
PGC-4064R | Recombinant Rat PGC Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
PGC-132H | Native Human Pepsinogen II | +Inquiry |
◆ Lysates | ||
PGC-1705RCL | Recombinant Rat PGC cell lysate | +Inquiry |
PGC-2169HCL | Recombinant Human PGC cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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