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Active Native Human CAPN1

Cat.No. : CAPN1-8448H
  • Specification
  • Gene Information
  • Related Products
Description : Ca2+-dependent cysteine proteinase with low Ca2+ requirement (half maximal activation = 2 μM). Participates in the ATP release reaction of platelets stimulated with thrombin. Involves in apoptosis activation.
Source : Human
Species : Human
Form : In 20 mM imidazole-HCl, 5 mM β-mercaptoethanol, 1 mM EDTA, 1 mM EGTA, 30% glycerol, pH 6.8.
Bio-activity : >1000 units/mg protein
Molecular Mass : 112.0 kDa
Purity : ≥95% by SDS - PAGE
Storage : Store at –70°C, stable for at least 1 year as supplied. Avoid freeze/thaw cycles.
Shipping : gel pack
Gene Name : CAPN1 calpain 1, (mu/I) large subunit [ Homo sapiens ]
Official Symbol : CAPN1
Synonyms : CAPN1; calpain 1, (mu/I) large subunit; calpain-1 catalytic subunit; CANP; CANPL1; muCANP; muCL; CANP 1; calpain mu-type; micromolar-calpain; calpain-1 large subunit; calpain, large polypeptide L1; calcium-activated neutral proteinase 1; cell proliferation-inducing protein 30; cell proliferation-inducing gene 30 protein; CANP1;
Gene ID : 823
mRNA Refseq : NM_001198868
Protein Refseq : NP_001185797
MIM : 114220
UniProt ID : P07384
Chromosome Location : 11q13
Pathway : Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Focal Adhesion, organism-specific biosystem; Integrin-mediated cell adhesion, organism-specific biosystem; Protein processing in endoplasmic reticulum, organism-specific biosystem;
Function : calcium ion binding; calcium-dependent cysteine-type endopeptidase activity; peptidase activity; protein binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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