Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Active Recombinant Human Thrombomodulin, His-tagged

Cat.No. : THBD-2602H
Product Overview : Recombinant Human THBD (Ala19­Ser515) fused with a C­terminal and 6­His tag, was expressed in Mouse NSO Cells.
  • Specification
  • Gene Information
  • Related Products
Cat. No. : THBD-2602H
Description : The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia.
Source : Mammalian cells
Molecular Mass : 53 kDa
Predicted N terminal : Ala19
Formulation : Supplied as a 0.2 μm filtered solution in Tris and NaCl.
Purity : >95%, by SDS­PAGE under reducing conditions and visualized by silver stain.
Activity : Measured by its ability to mediate thrombin activation of protein C. The specific activity is >50 pmol/min/µg, as measured under the described conditions.
EndotoxinLevel : <1.0 EU per 1 μg of the protein by the LAL method.
Storage : 6 months from date of receipt, ­20 to ­70 °C as supplied. Avoid repeated freeze­thaw cycles.
OfficialSymbol : THBD
Gene Name : THBD thrombomodulin [ Homo sapiens ]
Synonyms : THBD; thrombomodulin; TM; THRM; AHUS6; CD141; fetomodulin; CD141 antigen
Gene ID : 7056
mRNA Refseq : NM_000361
Protein Refseq : NP_000352
MIM : 188040
UniProt ID : P07204
Chromosome Location : 20p11.2
Pathway : Complement and coagulation cascades; Hemostasis
Function : calcium ion binding; protein binding; receptor activity; transmembrane receptor activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All THBD Products

Required fields are marked with *

My Review for All THBD Products

Required fields are marked with *

0

Inquiry Basket

cartIcon
logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends