Recombinant Human Forkhead box P3, GST-tagged

• Cat.No.: FOXP3-51H
• Product Overview: Recombinant Human FOXP3 (1 aa. - 431 aa.) protein fused with a ~26kD N-terminal GST tag was expressed.

Specification

• Cat. No.: FOXP3-51H
• Description: The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
• Molecular Mass: ~26kD
• Immunogen: This protein is not active and should not be used for experiments requiring activity.
• Uses: Western blot, ELISA. This protein has not been tested for any functionality. This product may contain endotoxins and is not suitable for use with live cells.
• Applications: WB; ELISA; PA
• Storage: Store at -80°C. Avoid freeze-thaw cycles.
• OfficialSymbol: FOXP3

Gene Information

• Gene Name: FOXP3 forkhead box P3 [ Homo sapiens ]
• Synonyms: FOXP3; forkhead box P3; JM2; AIID; IPEX; PIDX; XPID; DIETER; forkhead box protein P3; scurfin; FOXP3delta7; immunodeficiency, polyendocrinopathy, enteropathy, X-linked; immune dysregulation, polyendocrinopathy, enteropathy, X-linked
• Gene ID: 50943
• mRNA Refseq: NM_014009
• Protein Refseq: NP_054728
• MIM: 300292
• UniProt ID: Q9BZS1
• Chromosome Location: Xp11.23
• Pathway: Calcineurin-regulated NFAT-dependent transcription in lymphocytes; IL2 signaling events mediated by STAT5
• Function: DNA bending activity; NF-kappaB binding; NFAT protein binding; chromatin binding; double-stranded DNA binding