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Active Recombinant Human Glypican 1, His-tagged

Cat.No. : GPC1-152H
  • Specification
  • Gene Information
  • Related Products
ProductOverview : Recombinant Human Glypican 1(Asp24-Ser530), fused with a C-terminal 6-His tag, was expressed in Mouse NSO Cells.
Description : Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation.
Species : Human
Source : Mammalian cells
Form : Lyophilized from a 0.2 µm filtered solution in PBS.
Purity : > 95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Bio-activity : Measured by its binding ability in a functional ELISA. Immobilized rhGlypican 1 at 3 µg/mL (100 µL/well) will bind rhFGF-basic with an apparent KD < 1 nM.
EndotoxinLevel : < 0.10 EU per 1 μg of the protein by the LAL method.
PredictedN terminal : Asp24
MolecularMass : The recombinant protein has a calculated Molecular Mass of 56.8 kDa, In SDS-PAGE under reducing conditions the apparent molecular mass of the protein is approximately 60 kDa.
Reconstitution : Reconstitute at 500 µg/mL in sterile PBS.
Storage : Store it under sterile conditions at -20 ~ -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Gene Name : GPC1 glypican 1 [ Homo sapiens ]
Official Symbol : GPC1
Synonyms : GPC1; glypican 1; glypican-1; glypican; glypican proteoglycan 1
Gene ID : 2817
mRNA Refseq : NM_002081
Protein Refseq : NP_002072
MIM : 600395
UniProt ID : P35052
Chromosome Location : 2q35-q37
Pathway : Activation of Rac, organism-specific biosystem; Axon guidance, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Glypican 1 network, organism-specific biosystem; Glypican pathway, organism-specific biosystem
Function : heparan sulfate proteoglycan binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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