Recombinant Mouse Ptpn6, His-GST tagged
Cat.No. : | Ptpn6-8685M |
Product Overview : | Recombinant Mouse Ptpn6 (P29351-2) (Ala207-Lys597), fused with the N-terminal polyhistidine-tagged GST tag, was produced in Baculovirus-Insect cells. |
- Specification
- Gene Information
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Source : | Baculovirus-Insect cells |
Species : | Mouse |
Tag : | His-GST |
Predicted N Terminal : | Met |
Form : | Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 7.0, 10% glycerolNormally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. |
Molecular Mass : | The recombinant mouse PTPN6/GST chimera consists of 628 amino acids and has a calculated molecular mass of 72.7 kDa. The recombinant protein migrates as an approximately 63 kDa band in SDS-PAGE under reducing conditions. |
Endotoxin : | < 1.0 eu per μg of the protein as determined by the LAL method. |
Purity : | >85 % as determined by SDS-PAGE |
Stability : | Samples are stable for up to twelve months from date of receipt at -70oC. |
Storage : | Store it under sterile conditions at -20oC~-70oC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | Ptpn6 protein tyrosine phosphatase, non-receptor type 6 [ Mus musculus ] |
Official Symbol : | Ptpn6 |
Gene ID : | 15170 |
mRNA Refseq : | NM_001077705 |
Protein Refseq : | NP_001071173 |
Products Types
◆ Recombinant Protein | ||
PTPN6-3129H | Recombinant Human PTPN6 Protein, MYC/DDK-tagged | +Inquiry |
Ptpn6-1102M | Recombinant Mouse Ptpn6 Protein, MYC/DDK-tagged | +Inquiry |
PTPN6-1802H | Recombinant Human PTPN6 Protein, His (Fc)-Avi-tagged | +Inquiry |
PTPN6-0698H | Recombinant Human PTPN6 Protein (M1-K595), His/Strep tagged | +Inquiry |
PTPN6-4494R | Recombinant Rat PTPN6 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
PTPN6-001MCL | Recombinant Mouse PTPN6 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionPTPN6 acts as a phosphatase, removing phosphate groups from specific tyrosine residues in signaling molecules, thereby downregulating immune cell activation.
Yes, PTPN6 modulation is being explored as a potential target for immunotherapies aimed at enhancing or suppressing immune responses based on the clinical context.
PTPN6 negatively regulates T cell receptor signaling, and its modulation can have implications in controlling excessive immune responses seen in autoimmune diseases.
Yes, PTPN6 is being studied in diseases like rheumatoid arthritis, lupus, and certain types of leukemia and lymphoma.
Researchers are exploring small molecule inhibitors and gene therapies to modulate PTPN6 activity, with potential applications in autoimmune disorders and cancer treatment.
Customer Reviews (3)
Write a reviewStructural biology researchers can leverage its properties to better understand the three-dimensional architecture and conformational changes of proteins, gaining valuable insights into their function and interactions.
PTPN6 protein is highly recommended for various research applications, including ELISA and protein electron microscopy structure analysis.
PTPN6 protein might have biomarker properties, meaning its levels or activity could be indicative of disease progression or treatment response.
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