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Native Human SERPINA3

Cat.No. : SERPINA3-8349H
Product Overview : Native Human SERPINA3 was purified from Pooled normal human serum.
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  • Gene Information
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Description : ACT is a chronic acute phase marker and serine protease inhibitor of 68 kDa and pI between 3.75 and 4.0. ACT can complex with PSA to form the PSA-ACT complex, which is used as an indicator of tumor mass and clinical stage analysis of prostate cancer.Chronic acute phase marker and serine protease inhibitor of 68 kDa and pI between 3.75 and 4.0. ACT can complex with PSA to form PSA-ACT complex which is used as an indicator of tumour mass and clinical stage of prostate cancer.
Source : Pooled normal human serum
Species : Human
Form : Lyophilised from 0.02M NH4HCO3. May contain traces of buffer salts.
Molecular Mass : 68 kDa
Purity : >99%
Gene Name : SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 [ Homo sapiens ]
Official Symbol : SERPINA3
Synonyms : SERPINA3; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3; AACT, alpha 1 antichymotrypsin , serine (or cysteine) proteinase inhibitor, clade A (alpha 1 antiproteinase, antitrypsin), member 3; alpha-1-antichymotrypsin;
Gene ID : 12
mRNA Refseq : NM_001085
Protein Refseq : NP_001076
MIM : 107280
UniProt ID : P01011
Chromosome Location : 14q32.1
Pathway : Selenium Pathway, organism-specific biosystem;
Function : DNA binding; peptidase inhibitor activity; protein binding; serine-type endopeptidase inhibitor activity; serine-type endopeptidase inhibitor activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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What are the physiological roles of Serpina3n? 10/13/2022

Serpina3n plays significant roles in various physiological processes, including modulation of the complement cascade, apoptosis, wound healing, and potential implications in Alzheimer's disease.

What is the significance of Serpina3n in pathologies? 03/31/2022

Recent studies have reported significant roles of Serpina3n during various pathologies, particularly in central nervous system (CNS) insults, making it a potential therapeutic target.

What is the aim of literature drawing together Serpina3n applications? 03/26/2021

The aim is to compile literature shedding light on the potential therapeutic applications of Serpina3n/SERPINA3 in various diseases. Additionally, a brief comparison between murine Serpina3n and its human ortholog SERPINA3 (α1-antichymotrypsin) is provided to account for their biological roles and significance.

Are the full range of Serpina3n applications known? 07/21/2020

The full range of potential applications of Serpina3n is yet to be fully revealed, but its reported implications, especially in CNS insults, suggest potential therapeutic applications.

What is Serpina3n? 05/06/2020

Serpina3n is a secretory serine protease inhibitor belonging to clade "a" with unique structural and physiological characteristics. |

How does Serpina3n inhibit proteases? 05/12/2017

Serpina3n inhibits a wide range of proteases, contributing to its diverse physiological roles.

To which clade does Serpina3n belong? 03/07/2016

Serpina3n belongs to clade "a" of serine protease inhibitors. |

Customer Reviews (3)

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Reviews
03/14/2022

    The product's impact extended to data analysis, with intuitive tools for interpreting experimental results.

    06/14/2020

      The longevity of the product's effects allowed us to study cellular responses over extended timeframes.

      10/31/2017

        We found that the product's support for data analysis and visualization significantly expedited our research.

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