Recombinant Human Tissue Factor, Non-Lipidated

• Cat.No.: F3-18H
• Product Overview: TF-263 is full length human tissue factor, produced in a recombinant eukaryotic cell expression system. The 263 amino acid full length tissue factor protein is comprised of an extracellular, a transmembrane and a cytoplasmic domain.

Specification

• Description: Tissue Factor (TF) is a cell-surface protein present on endothelial cells and monocytes which is involved in coagulation and inflammation. TF is the primary initiator of the blood coagulation protease cascade functioning as a receptor and cofactor for the extrinsic tenase complex.
• Species: Human
• Form: Supplied as a solution containing 20mM TRIS-HCL (pH 8.0), 200 mM NaCl, 1% glucoside, and<0.1% sodium azide.>
• Molecular Mass: 35-38 kDa
• Purity: Greater than 90% by SDS-PAGE
• Storage: Store protein in aliquots frozen at -20°C or colder, avoid multiple freeze-thaw cycles.

Gene Information

• Gene Name: F3 coagulation factor III (thromboplastin, tissue factor) [ Homo sapiens ]
• Official Symbol: F3
• Synonyms: F3; coagulation factor III (thromboplastin, tissue factor); tissue factor; CD142; TF; TFA; FLJ17960
• Gene ID: 2152
• mRNA Refseq: NM_001178096
• Protein Refseq: NP_001171567
• MIM: 134390
• UniProt ID: P13726
• Chromosome Location: 1p22-p21
• Pathway: Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Extrinsic Pathway, organism-specific biosystem; Formation of Fibrin Clot (Clotting Cascade), organism-specific biosystem; Hemostasis, organism-specific biosystem
• Function: cell surface binding; phospholipid binding; protease binding; protein binding