Recombinant Human GAD2 Protein, His-tagged
Cat.No. : | GAD2-9169H |
Product Overview : | Recombinant human GAD2 protein with a His-tag was expressed in E. coli |
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- Specification
- Gene Information
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Description : | This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Molecular Mass : | The protein has a calculated MW of 67.5 kDa. |
AA Sequence : | MGSSHHHHHHSSGLVPRGSHMASPG SGFWSFGSEDGSGDSENPGTARAWC QVAQKFTGGIGNKLCALLYGDAEKP AESGGSQPPRAAARKAACACDQKPC SCSKVDVNYAFLHATDLLPACDGER PTLAFLQDVMNILLQYVVKSFDRST KVIDFHYPNELLQEYNWELADQPQN LEEILMHCQTTLKYAIKTGHPRYFN QLSTGLDMVGLAADWLTSTANTNMF TYEIAPVFVLLEYVTLKKMREIIGW PGGSGDGIFSPGGAISNMYAMMIAR FKMFPEVKEKGMAALPRLIAFTSEH SHFSLKKGAAALGIGTDSVILIKCD ERGKMIPSDLERRILEAKQKGFVPF LVSATAGTTVYGAFDPLLAVADICK KYKIWMHVDAAWGGGLLMSRKHKWK LSGVERANSVTWNPHKMMGVPLQCS ALLVREEGLMQNCNQMHASYLFQQD KHYDLSYDTGDKALQCGRHVDVFKL WLMWRAKGTTGFEAHVDKCLELAEY LYNIIKNREGYEMVFDGKPQHTNVC FWYIPPSLRTLEDNEERMSRLSKVA PVIKARMMEYGTTMVSYQPLGDKVN FFRMVISNPAATHQDIDFLIEEIER LGQDL |
Endotoxin : | <1 EU/μg |
Purity : | >90% |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | Lyophilized from sterile PBS, pH 8.0, 5% trehalose, 5% mannitol. |
Gene Name : | GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) [ Homo sapiens (human) ] |
Official Symbol : | GAD2 |
Synonyms : | GAD2; glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa); glutamate decarboxylase 2 (pancreatic islets and brain, 65kD); glutamate decarboxylase 2; GAD65; GAD-65; 65 kDa glutamic acid decarboxylase; Glutamate decarboxylase-2 (pancreas); glutamate decarboxylase 65 kDa isoform; MGC161605; MGC161607; |
Gene ID : | 2572 |
mRNA Refseq : | NM_000818 |
Protein Refseq : | NP_000809 |
MIM : | 138275 |
UniProt ID : | Q05329 |
Products Types
◆ Recombinant Protein | ||
GAD2-2114R | Recombinant Rat GAD2 Protein, His (Fc)-Avi-tagged | +Inquiry |
GAD2-1556H | Recombinant Human GAD2 Protein, His-tagged | +Inquiry |
GAD2-4655H | Recombinant Human GAD2 Protein, GST-tagged | +Inquiry |
GAD2-1557H | Recombinant Human GAD2 Protein, His-tagged | +Inquiry |
GAD2-956H | Recombinant Human GAD2 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
GAD2-001MCL | Recombinant Mouse GAD2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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