Recombinant Mouse Kcnj6 (consisting of residues 52-380, constitutively active mutant)
Cat.No. : | Kcnj6-9171M |
Product Overview : | Recombinant Mouse Kcnj6 (consisting of residues 52-380 , constitutively active mutant), was expressed in Pichia pastoris and purified by Affinity chromatography, Superdex-200 gel filtration. |
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- Gene Information
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Description : | Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and may be involved in the regulation of insulin secretion by glucose. It associates with two other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex. |
Source : | Pichia pastoris |
Species : | Mouse |
Form : | 20 mM Tris-HCl (pH 7.5), 150 mM KCl, 0.2% (w/v) DM ,20 mM DTT, and 1 mM EDTA |
Molecular Mass : | Predicts a molecular mass of 37KDa. As a result of transmembrane protein, it migrates approximately 33~40 KDa in SDS-PAGE under non-reducing conditions. |
Protein length : | 329 amino acids(residues 52-380) |
Purity : | >95% as determined by SDS-PAGE |
Storage : | Can be stored at +4℃ short term. For long term storage, store at -20℃ |
Concentration : | 0.54 mg/ml |
Gene Name : | Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 [ Mus musculus ] |
Official Symbol : | Kcnj6 |
Synonyms : | KCNJ6; potassium inwardly-rectifying channel, subfamily J, member 6; G protein-activated inward rectifier potassium channel 2; GIRK-2; inward rectifier K(+) channel Kir3.2; potassium inwardly-rectifying channel J6; potassium channel, inwardly rectifying subfamily J member 6; wv; BIR1; GIRK2; KATP2; KCNJ7; Kir3.2; weaver; |
Gene ID : | 16522 |
mRNA Refseq : | NM_001025584 |
Protein Refseq : | NP_001020755 |
Pathway : | Activation of G protein gated Potassium channels, organism-specific biosystem; Activation of GABAB receptors, organism-specific biosystem; Cholinergic synapse, organism-specific biosystem; Dopaminergic synapse, organism-specific biosystem; Dopaminergic synapse, conserved biosystem; G protein gated Potassium channels, organism-specific biosystem; GABA B receptor activation, organism-specific biosystem; |
Function : | G-protein activated inward rectifier potassium channel activity; G-protein alpha-subunit binding; inward rectifier potassium channel activity; ion channel activity; voltage-gated ion channel activity; |
Products Types
◆ Recombinant Protein | ||
KCNJ6-355H | Recombinant Human KCNJ6 Protein, MYC/DDK-tagged | +Inquiry |
Kcnj6-1260M | Recombinant Mouse Kcnj6 Protein, MYC/DDK-tagged | +Inquiry |
KCNJ6-2859R | Recombinant Rat KCNJ6 Protein, His (Fc)-Avi-tagged | +Inquiry |
KCNJ6-3203R | Recombinant Rat KCNJ6 Protein | +Inquiry |
KCNJ6-259H | Recombinant Human KCNJ6, GST-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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