Recombinant Human AKT2, His-tagged
Cat.No. : | AKT2-165H |
Product Overview : | Recombinant full-length human AKT2 was co-expressed with PDK1 by baculovirus infection in Sf9 insect cells. |
- Specification
- Gene Information
- Related Products
Cat. No. : | AKT2-165H |
Description : | This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. |
Source : | Baculovirus |
Molecular Mass : | 57 kDa |
Specific Activity : | 7 pmol/min/µg. The enzyme reaction is conducted in a buffer containing 50 mM HEPES (pH7.5), 10 mM MgCl2, 1 mM EGTA, 200 µM ATP, 0.01% Brij-35, and 2 µM substrate at 30 oC for 1 hour. |
Application : | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
Purity : | ≥90% |
Fomulated in : | 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 250 mM imidazole, 20% glycerol, and 3 mM DTT. |
Stability : | >6 months at –80°C |
OfficialSymbol : | AKT2 |
Gene Name : | AKT2 v-akt murine thymoma viral oncogene homolog 2 [ Homo sapiens ] |
Synonyms : | AKT2; v-akt murine thymoma viral oncogene homolog 2; PKBB; PRKBB; PKBBETA; RAC-BETA; AKT2 kinase; rac protein kinase beta; Murine thymoma viral (v-akt) homolog-2; EC 2.7.11.1; RAC-beta serine/threonine-protein kinase; RAC-PK-beta; Protein kinase Akt-2; Protein kinase B, beta; PKB beta |
Gene ID : | 208 |
mRNA Refseq : | NM_001626 |
Protein Refseq : | NP_001617 |
MIM : | 164731 |
UniProt ID : | P31751 |
Chromosome Location : | 19q13.1-q13.2 |
Pathway : | Acute myeloid leukemia; Adipocytokine signaling pathway; Apoptosis; B cell receptor signaling pathway; Chemokine signaling pathway; Chronic myeloid leukemia; Colorectal cancer; Endometrial cancer; ErbB signaling pathway |
Function : | ATP binding; nucleotide binding; protein binding; protein serine/threonine kinase activity; transferase activity |
Products Types
◆ Recombinant Protein | ||
AKT2-125R | Recombinant Rhesus Macaque AKT2 Protein, His (Fc)-Avi-tagged | +Inquiry |
AKT2-0083H | Recombinant Human AKT2 Protein (N2-E481), GST tagged | +Inquiry |
AKT2-307H | Recombinant Human AKT2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Akt2-567M | Recombinant Mouse Akt2 Protein, MYC/DDK-tagged | +Inquiry |
AKT2-0082H | Recombinant Human AKT2 Protein (N2-E481), Tag Free | +Inquiry |
◆ Lysates | ||
AKT2-8927HCL | Recombinant Human AKT2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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