Active Recombinant Human MMP3, His-tagged
Cat.No. : | MMP3-200H |
Product Overview : | Recombinant Human MMP3 is a proform of the Human MMP3 [Tyr18-Cys477 (Lys45Glu)] and fused with a ployhistide tag at the C-terminus. It was expressed in HEK 293Cells. |
- Specification
- Gene Information
- Related Products
Cat. No. : | MMP3-200H |
Description : | MMP-3 enzyme is also known as Stromelysin-1or as Transin-1 which hydrolyzes natural collagen at physiological pH and temperature. It dissolves the intervertebral nucleus pulposus and annulus fibrosus of Herniated Lumbar Intervertebral Disk. MMP-3 hydrolyzes components of the extracellular matrix like proteoglycan, laminin, fibronectin, gelatin and collagen types III, IV and IX. It also activates pro-MMP-9 and pro-MMP-8 and superactivates plasmin activated MMP-1. MMP-3 is secreted as a latent proenzyme and is activated by a variety of proteinases, e.g. plasmin, trypsin, chymotrypsin, cathepsin G or human neutrophil elastase. MMP-3 was found to be capable of activating the precursor of IL1-beta. |
Source : | HEK293 Cells |
Molecular Mass : | 52kDa |
Purity : | Greater than 95% as determined by SDS-PAGE. |
Formulation : | Supplied as a 0.2µm filtered solution in Tris, NaCl and Brij35. |
Bio-activity : | The activity was measured by its ability to cleave the fluorogenic peptide substrate, Mca-RPKPVE-Nval-WRK(Dnp)-NH2. The specific activity is > 150 pmoles/min/µg. |
Storage : | Store at -20°C. Avoid multiple freeze-thaw cycles. |
OfficialSymbol : | MMP3 |
Gene Name : | MMP3 matrix metallopeptidase 3 (stromelysin 1, progelatinase) [ Homo sapiens ] |
Synonyms : | matrix metallopeptidase 3 (stromelysin 1, progelatinase); SL-1; STMY; STR1; CHDS6; MMP-3; STMY1; MGC126102; transin-1; MMP3; MGC126103; matrix metalloproteinase 3; CHDS6; Transin-1; proteoglycanase; MGC126104; Matrix metalloproteinase-3; EC 3.4.24.17 |
Gene ID : | 4314 |
mRNA Refseq : | NM_002422 |
Protein Refseq : | NP_002413 |
MIM : | 185250 |
UniProt ID : | P08254 |
Chromosome Location : | 11q22.3 |
Function : | calcium ion binding; metalloendopeptidase activity; peptidase activity; zinc ion binding |
Products Types
◆ Recombinant Protein | ||
MMP3-5433H | Recombinant Human MMP3 Protein, GST-tagged | +Inquiry |
MMP3-1123H | Recombinant Human MMP3 Protein, His-tagged | +Inquiry |
MMP3-1420H | Recombinant Human MMP3 Protein, His (Fc)-Avi-tagged | +Inquiry |
MMP3-240H | Recombinant Human MMP3 Protein, His-tagged(C-ter) | +Inquiry |
Mmp3-10594M | Recombinant Mouse Mmp3 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
MMP3-26C | Collagenase Type 3 Protein | +Inquiry |
◆ Lysates | ||
MMP3-4273HCL | Recombinant Human MMP3 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-2213 | MMP-3 Activity Fluorometric Assay Kit | +Inquiry |
Kit-0589 | MMP-3 Activity Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket