Active Recombinant Human GDF3
Cat.No. : | GDF3-02H |
Product Overview : | Recombinant human GDF-3 is a 26.0 kDa non-disulfide-linked homodimer containing two 114 amino acid polypeptide chains. Manufactured using all non-animal reagents. |
- Specification
- Gene Information
- Related Products
Description : | GDF-3 is a member of the TGF-β superfamily of growth and differentiation factors, and is highly homologous to GDF-9. Unlike most TGF-β family members, GDF-3 and GDF-9 are not disulfide-linked dimers. GDF-3 is expressed in adult bone marrow, spleen, thymus, and adipose tissue. The expression of GDF-3 is upregulated in high-fat-fed wild-type FABP4/aP2 null mice and was associated with obesity, but not with the related hyperglycemia/hyperinsulinemia which characterizes Type 2 diabetes. |
Source : | E. coli |
Species : | Human |
Bio-activity : | Determined by its ability to inhibit induced alkaline phosphatase production by ATDC-5 chondrogenic cells. The ED50 for this effect is 100-150 ng/ml. |
AA Sequence : | AAIPVPKLSC KNLCHRHQLF INFRDLGWHK WIIAPKGFMA NYCHGECPFS LTISLNSSNY AFMQALMHAV DPEIPQAVCI PTKLSPISML YQDNNDNVIL RHYEDMVVDE CGCG |
Purity : | Greater than 98% by SDS-PAGE gel and HPLC analyses. |
Storage : | Store at -20°C. Avoid repeated freeze-thaw cycles. |
Gene Name : | GDF3 growth differentiation factor 3 [ Homo sapiens ] |
Official Symbol : | GDF3 |
Synonyms : | GDF3; growth differentiation factor 3; growth/differentiation factor 3; GDF-3; KFS3; MCOP7; MCOPCB6; |
Gene ID : | 9573 |
mRNA Refseq : | NM_020634 |
Protein Refseq : | NP_065685 |
MIM : | 606522 |
UniProt ID : | Q9NR23 |
Chromosome Location : | 12p13.1 |
Function : | cytokine activity; growth factor activity; |
Products Types
◆ Recombinant Protein | ||
Gdf3-273R | Recombinant Rat Gdf3 Protein, His-tagged | +Inquiry |
GDF3-4825H | Recombinant Human GDF3 Protein, GST-tagged | +Inquiry |
GDF3-3520M | Recombinant Mouse GDF3 Protein, His (Fc)-Avi-tagged | +Inquiry |
Gdf3-272M | Recombinant Mouse Gdf3 Protein, His-tagged | +Inquiry |
GDF3-271H | Recombinant Human GDF3 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
GDF3-5969HCL | Recombinant Human GDF3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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