Recombinant Human AIM2, GST-tagged

• Cat.No.: AIM2-9507H
• Product Overview: Recombinant Human AIM2 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 1-343a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: AIM2 absent in melanoma 2 [ Homo sapiens ]
• Official Symbol: AIM2
• Synonyms: AIM2; absent in melanoma 2; interferon-inducible protein AIM2; PYHIN4
• Gene ID: 9447
• mRNA Refseq: NM_004833
• Protein Refseq: NP_004824
• MIM: 604578
• UniProt ID: O14862
• Chromosome Location: 1q22
• Pathway: Cytosolic DNA-sensing pathway, organism-specific biosystem; Cytosolic DNA-sensing pathway, conserved biosystem; Immune System, organism-specific biosystem; Inflammasomes, organism-specific biosystem; Innate Immune System, organism-specific biosystem; Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, organism-specific biosystem; The AIM2 inflammasome, organism-specific biosystem
• Function: double-stranded DNA binding