Recombinant Human AP3M1, GST-tagged
Cat.No. : | AP3M1-9722H |
Product Overview : | Recombinant Human AP3M1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Description : | The protein encoded by this gene is the medium subunit of AP-3, which is an adaptor-related protein complex associated with the Golgi region as well as more peripheral intracellular structures. AP-3 facilitates the budding of vesicles from the Golgi membrane and may be directly involved in protein sorting to the endosomal/lysosomal system. AP-3 is a heterotetrameric protein complex composed of two large subunits (delta and beta3), a medium subunit (mu3), and a small subunit (sigma 3). Mutations in one of the large subunits of AP-3 have been associated with the Hermansky-Pudlak syndrome, a genetic disorder characterized by defective lysosome-related organelles. Alternatively spliced transcript variants encoding the same protein have been observed. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | C-term-200a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | AP3M1 adaptor-related protein complex 3, mu 1 subunit [ Homo sapiens ] |
Official Symbol : | AP3M1 |
Synonyms : | AP3M1; adaptor-related protein complex 3, mu 1 subunit; AP-3 complex subunit mu-1; mu3A-adaptin; mu-adaptin 3A; AP-3 adapter complex mu3A subunit; clathrin adaptor complex AP3, mu-3A subunit; adapter-related protein complex 3 mu-1 subunit; MGC22164; |
Gene ID : | 26985 |
mRNA Refseq : | NM_012095 |
Protein Refseq : | NP_036227 |
MIM : | 610366 |
UniProt ID : | Q9Y2T2 |
Chromosome Location : | 10q22.1-q22.3 |
Pathway : | Association of TriC/CCT with target proteins during biosynthesis, organism-specific biosystem; Chaperonin-mediated protein folding, organism-specific biosystem; Lysosome, organism-specific biosystem; Lysosome, conserved biosystem; Metabolism of proteins, organism-specific biosystem; Protein folding, organism-specific biosystem; |
Function : | protein binding; |
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AP3M1-657H | Recombinant Human AP3M1 protein, GST-tagged | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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