Recombinant Human APCS, GST-tagged

• Cat.No.: APCS-9734H
• Product Overview: Recombinant Human APCS protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 20-223a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: APCS amyloid P component, serum [ Homo sapiens ]
• Official Symbol: APCS
• Synonyms: APCS; amyloid P component, serum; serum amyloid P-component; 9.5S alpha 1 glycoprotein; MGC88159; pentaxin related; PTX2; SAP; pentaxin-related; 9.5S alpha-1-glycoprotein
• Gene ID: 325
• mRNA Refseq: NM_001639
• Protein Refseq: NP_001630
• MIM: 104770
• UniProt ID: P02743
• Chromosome Location: 1q21-q23
• Pathway: Amyloids, organism-specific biosystem; Disease, organism-specific biosystem
• Function: metal ion binding; sugar binding; unfolded protein binding