Recombinant Human APLF, GST-tagged

• Cat.No.: APLF-9742H
• Product Overview: Recombinant Human APLF protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: C2ORF13 is a component of the cellular response to chromosomal DNA single- and double-strand breaks (Iles et al., 2007 [PubMed 17353262]).
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: C-term-350a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: APLF aprataxin and PNKP like factor [ Homo sapiens ]
• Official Symbol: APLF
• Synonyms: APLF; aprataxin and PNKP like factor; C2orf13, chromosome 2 open reading frame 13; aprataxin and PNK-like factor; MGC47799; XRCC1-interacting protein 1; PNK and APTX-like FHA protein; aprataxin- and PNK-like factor; apurinic-apyrimidinic endonuclease APLF; PNK and APTX-like FHA domain-containing protein; APFL; PALF; Xip1; C2orf13; FLJ16593
• Gene ID: 200558
• mRNA Refseq: NM_173545
• Protein Refseq: NP_775816
• MIM: 611035
• UniProt ID: Q8IW19
• Chromosome Location: 2p14
• Function: 3-5 exonuclease activity; DNA-(apurinic or apyrimidinic site) lyase activity; endodeoxyribonuclease activity; lyase activity; metal ion binding; nucleotide binding; protein binding