Recombinant Human BAG3, His-tagged
Cat.No. : | BAG3-10125H |
Product Overview : | Recombinant Human BAG3 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose. |
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Description : | BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. |
Source : | E.coli |
Species : | Human |
Tag : | His |
Protein length : | 275-575a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol. |
Gene Name : | BAG3 BCL2-associated athanogene 3 [ Homo sapiens ] |
Official Symbol : | BAG3 |
Synonyms : | BAG3; BCL2-associated athanogene 3; BAG family molecular chaperone regulator 3; docking protein CAIR-1; BCL2-binding athanogene 3; bcl-2-binding protein Bis; bcl-2-associated athanogene 3; BAG-family molecular chaperone regulator-3; BIS; BAG-3; CAIR-1; MGC104307; |
Gene ID : | 9531 |
mRNA Refseq : | NM_004281 |
Protein Refseq : | NP_004272 |
MIM : | 603883 |
UniProt ID : | O95817 |
Chromosome Location : | 10q25.2-q26.2 |
Function : | chaperone binding; |
Products Types
◆ Recombinant Protein | ||
BAG3-097H | Recombinant Human BAG3 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
BAG3-335R | Recombinant Rhesus Macaque BAG3 Protein, His (Fc)-Avi-tagged | +Inquiry |
BAG3-293H | Recombinant Human BAG3 Protein, His-tagged | +Inquiry |
BAG3-2138H | Recombinant Human BAG3 Protein, MYC/DDK-tagged | +Inquiry |
Bag3-1817M | Recombinant Mouse Bag3 Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
BAG3-56HCL | Recombinant Human BAG3 lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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