Recombinant Human BCMO1, His-tagged

• Cat.No.: BCMO1-10192H
• Product Overview: Recombinant Human BCMO1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Description: Vitamin A metabolism is important for vital processes such as vision, embryonic development, cell differentiation, and membrane and skin protection. The protein encoded by this gene is a key enzyme in beta-carotene metabolism to vitamin A. It catalyzes the oxidative cleavage of beta,beta-carotene into two retinal molecules.
• Source: E.coli
• Species: Human
• Tag: His
• Protein length: 199-547a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: BCMO1 beta-carotene 15,15-monooxygenase 1 [ Homo sapiens ]
• Official Symbol: BCMO1
• Synonyms: BCMO1; beta-carotene 15,15-monooxygenase 1; BCDO, BCDO1, beta carotene 15, 15 dioxygenase 1; beta,beta-carotene 15,15-monooxygenase; BCMO; FLJ10730; beta-carotene dioxygenase 1; beta-carotene 15, 15-dioxygenase 1; BCO; BCDO; BCO1; BCDO1
• Gene ID: 53630
• mRNA Refseq: NM_017429
• Protein Refseq: NP_059125
• MIM: 605748
• UniProt ID: Q9HAY6
• Chromosome Location: 16q23.2
• Pathway: Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; Metabolism of steroid hormones and vitamins A and D, organism-specific biosystem; Retinol metabolism, organism-specific biosystem; Retinol metabolism, conserved biosystem; Vitamin A and carotenoid metabolism, organism-specific biosystem
• Function: beta-carotene 15,15-monooxygenase activity; beta-carotene 15,15-monooxygenase activity; metal ion binding; monooxygenase activity